What does an isolated high bilirubin suggest? (2)
haemolytic anaemia
Gilbert’s syndrome
What does an AST 2x greater than ALT suggest? (ie. AST:ALT 2:1)
Alcoholic liver disease
What does raised ALP and GGT suggest?
biliary pathology
What does ALT and AST in the 1000s suggest?
Hepatitis - toxic, ischaemic, viral
What does raised alpha-fetoprotein (AFP) suggest?
hepatocellular carcinoma
What does hypoalbuminaemia suggest?
liver failure
nephrotic syndrome
How do we test for synthetic liver function?
Look at clotting profile - if poor clotting then sythetic function reduced
