Flashcards in LMP301 Lecture 3: Fluid Balance Deck (135)
ECF can be subdivided into...
- Interstitial fluid (ISF)
How much ICF is there?
How much ECF is there?
How much plasma is there?
How much ISF is there?
ACE inhibitor = ?
angiotensin converting enzyme inhibitor
What are ACE inhibitors used for and how do they work?
Used for hypertension
Work by dilating blood vessels
What are the common electrolytes measured?
Where are electrolytes measured from?
Plasma and electrolytes are most abundant in...
Is it harder to do ECF or ICF measurement?
What are extracellular ions?
What are intracellular ions?
amount of solute in a solvent
amount of solute particles in a solvent (weight)
How to estimate osmolality?
Measure the most abundant solutes:
2[Na+] & [Glucose] & [Urea]
amount of solute particles in 1kg of water (WATER IS SOLVENT)
When measuring dilute aqueous solutions, the appropriate unit is...concentration / osmolality / osmolarity
One weakness of concentration measurements
Must take into account total volume of solvent (dehydrated might affect measurement of electrolytes)
Osmolarity is a passive / active process?
Define: oncotic pressure
Pressure in the capillaries
Walls of capillaries act as semi-permeable membrane, and proteins pull water into plasma.
Define: hydrostatic pressure
Pressure exerted by the heart when it pumps
Pushes fluid in vessels into ISF.
Oncotic pressure is balanced by...
Hydrostatic pressure is balanced by...
What might affect oncotic pressure?
- Injury: cause proteins in plasma to leak out
Typical input of water?
0.5 - 5L per day
Amount of output of water through renal processes?
0.5 - 4L per day
Amount of output of water through GI tract?
< 0.1 L per day
Amount of output of water through insensible loss?
0.5 - 1L per day