LMP301 Lecture 15: Liver Diseases Flashcards Preview

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Flashcards in LMP301 Lecture 15: Liver Diseases Deck (106)
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1

The liver has a small ___ and a big ____

left lobe
right lobe

2

Under the liver lies the...

gall bladder

3

___ brings blood from GI to the liver

hepatic portal vein

4

the hepatic vein flows into the...

superior vena cava

5

___ eliminates bile from liver

bile tract

6

____ mL of blood flow into the liver every minute. This is ___ of the CO

1300
1/4

7

___ constitutes 75% of the blood supplied to the liver

hepatic portal vein

8

___ constitutes 25% of blood supplied to the liver

hepatic artery

9

what carries blood directly to the liver?

hepatic artery

10

what indirectly carries blood to the liver?

hepatic portal vein (goes through stomach & intestines)

11

The liver is arranged into...

lobules

12

lobules are shaped like...

hexagon

13

the middle of a lobule is the...

central vein

14

what cells make up the liver?

hepatocytes

15

things from the central vein drain into ___ (connected by ___)

bile duct
bile canaliculus

16

Kupffer cells

- phagocytic cells in sinusoids
- remove foreign antigens
- antigen-antibody complex

17

what can be found on the outside of the lobule?

- hepatic artery
- hepatic portal vein
- bile duct

18

the hepatic portal vein drain into ___ (connected by ___)

central vein
sinusoid

19

hepatic artery flows into...

sinusoid

20

define: sinusoid

- space in the liver that contains O rich blood from hepatic artery & nutrient rich blood from portal vein
- also contains Kupffer cells

21

hepatocytes

- major cells in liver
- site of metabolic & synthetic functions

22

Ito / stellate cells

- normally store fat
- can produce collagen

23

which liver cells play an important role in liver pathology?

- Kupffer cells
- Ito cells

24

liver physiology (4)

1. energy metabolism / catabolism
2. synthetic functions
3. excretory & secretory functions
4. other

25

what is metabolized in the liver?

1. carbohydrate metabolism (glycogenolysis, gluconeogenesis)
2. protein metabolism (protein catabolism in AA)
3. lipid metabolism (FFA metabolism)

26

what is synthesized in the liver?

1. serum proteins
2. coagulation factors
4. lipids

27

serum proteins synthesized in the liver

- albumin
- a-1-antitrypsin
- hormone binding proteins

28

coagulation factors synthesized in the liver

- fibrinogen
- prothrombin
- clotting factors
- antithrombin

29

lipids synthesized in the liver

- cholesterol
- apolipoproteins
- triglycerides

30

besides it's main purpose, what other function do materials synthesized from the liver serve?

we can examine these in the body to see if there is something wrong with the liver