LP 6 Flashcards
(7 cards)
Which are the antioxidant vitamins?
A
C
E
Which are the liposoluble vitamins?
ADEK
Vit A chief functions include: ____; immunity; cellular growth; differentiation; commmunication; maintenance of ______ cells.
Vit A food sources include: Fish and ____ oil; milk; dairy and eggs, leafy greens, fortified cereals and grains.
Vit A deficiency most common symptom is ______ (greek for dry eye) with characteristic ____ spots.
Vit A toxicity is rare and only occurs above 10X the RDA. Look for _____ colored skin in these patients or increased _____ pressure. There is also an increased risk for cancer in smokers.
High dose Vit A has shown therapeutic effects for ______ and ____ disorders.
Interactions with _____ (induced fat malabsorption) and synthetic retinoids.
Vision
Epithelial
Liver
Xeropthalmia
Bitot’s
Orange
Intracranial
Measles
Skin
Orlistat
Vit C chief functions include: action as a _____ agent; cofactor in ____ synth; increases bioavailability/absorption of _____; antioxidant; regeneration of Vit E.
Vit C food sources include: citrus fruits; broccoli; peppers; cauliflower; cabage
Vit C deficiency can lead to ______ (think sailors); ____ deficiency anemia.
Vit C toxicity can cause diarrhea, GI discomfort, and ____ stones.
Diets rich in Vit C may decrease risk of cardiovascular disease and strokebc Vit C enhances _______.
Interactions include Niacin, Simvastatin, and _____ radiation (remember Vit C is an antioxidant, so it would reduce the effect of this radiation.)
Reducing agent
Collagen
Iron
Scurvy
Iron
Kidney stones
Vasodilation
Chemotherapy
Vit E chief functions include: inhibits ____ aggregation; immune enhancement; anti-______ (odd given that it enhances immune response).
Vit E food sources include: wheat germ, nuts, seeds and _____ oils.
Vit E deficiency is very rare but may cause: neuropathy, ataxia, skeletal _____, retinopathy, and impaired _____ response.
Vit E toxicity can lead to _______ stroke (not ischemic)
Vit E has been shown to decrease the risk of Age-related _____ ______ (ARMD).
Vit E interactions include: Strengthens the effects of anti-coagulants and anti-_______ aggregation (so it must lower the effect of which Vit?); Anticonvulsants _____ (increase or decrease?) vitamin E concentration.
Platelet
anti-inflammatory
Vegetable oils
Skeletal Myopathy
Immune
Hemorrhagic stroke
Age-related Macular Degeneration (ARMD)
Platelet aggregation, so it reduces the effects of Vit K
Decrease
Vit K chief functions include: ______ and Bone metabolism.
Vit K food sources include: K__ (1 or 2?) in leafy greens and some veg oils. K__ (1 or 2) in gut bacteria, animal products and _____ foods.
Vit K deficiency can cause: basically everything to do with hemorrhage and bruising and _____ colored stool. It can also contribute to _____ (think bone health).
Vit K toxicity: No such thing
Vit K has been shown to be essential for the carboxylation of a protein that prevents vascular ______. It has also been shown to decrease risk of ______ bc it is a cofactor for osteocalcin protein in bone.
Vit K interactions include: Vit K antagonists (warfarin), antibiotics (think about why that is), Orlistat (induced fat malabsorption), and ____ acid sequestrants (reduce Vit K absorption).
Coagulation
K1
K2
Fermented foods
Tarry black
Osteoporosis
Calcification
Osteoporosis
Bile acid sequestrants
Vit D chief functions include: the obvious bone health stuff as well as ______ and cardiovascular function.
Vit D significant food sources include: Fatty ____, fortified foods, and of course good ol’ ____light.
Vit D deficiency is implicated in ____ in children, osteomalacia and osteoporosis in adults.
Vit D toxicity can cause bone loss, ____ stones, vascular and tissue calcification as well as heart arrythmia.
Vit D has been shown to modulate T-cell responses and thus decrease _______ diseases.
Vit D interactions include: Steroids which reduce Ca++ absorption/Vit D metabolism, Orlistat (induced fat malabsorption), Anticonvulsants which increase the breakdown of Vit D and reduce _____ absorption.
Endocrine
Fish
Sunlight
Rickets
Kidney stones
Autoimmune
Ca++
