Lymphatic System Flashcards
(40 cards)
Structure of the lymphatic system
- Open circulatory system (has a start and end point rather than being continuous)
- Contains lymph fluid, lymph vessels, lymph glands, spleen, thymus, bone marrow, tonsils, adenoids, Peyer’s patches
Compare the lymphatic system with the CVS
- Both are circulatory systems as they transport fluid around the body
- CVS = closed (continuous loop) whereas lymphatic = open (has a start and end point)
- CVS = pump (heart) whereas lymphatic = no pump (other factors e.g. changes in
thoracic pressure and muscle contractions) - CVS = blood filtered by kidneys whereas lymphatic = lymph filtered by lymph nodes
What is A? Is it primary or secondary lymphatic tissue?
Adenoid - secondary
What is B? Is it primary or secondary lymphatic tissue?
Tonsils - secondary
What is C? Is it primary or secondary lymphatic tissue?
(Cervical) lymph node - secondary
What is D? Is it primary or secondary lymphatic tissue?
Thymus - primary
What is E and what is its function?
Thoracic duct
- Drains lymph from: the legs, abdominopelvic cavity, left arm and left halves of the thorax, head and neck
What is F? Is it primary or secondary lymphatic tissue?
Peyer’s patches - secondary
What is G? Is it primary or secondary lymphatic tissue?
Bone marrow - primary
What is H? Is it primary or secondary lymphatic tissue?
Spleen - secondary
What are lymphocytes and where are they formed and matured?
- Type of leukocyte (WBC), B cells produce antibodies to destroy pathogens whereas T cells directly destroy pathogens by releasing cytotoxic chemicals
- Both B & T lymphocytes are produced in bone marrow but B cells mature in bone marrow and T cells mature in the thymus.
Primary lymphoid tissue vs secondary lymphoid tissue
- Primary: site of lymphocyte formation and maturation (bone marrow and thymus)
- Secondary: sites where lymphocytes interact with and filter extracellular fluids such as plasma, tissue fluid and lymph (lymph nodes, spleen, tonsils, adenoids, Peyer’s patches)
Describe the structure and function of bone marrow
- S = primary lymphoid tissue inside spongy bone
- F = produce B & T lymphocytes, mature B lymphocytes (lymphoblast>lymphocyte)
What is the function of the thymus?
To mature T lymphocytes
Difference between lymph, tissue fluid and plasma
- Tissue fluid = leaked out of blood into surrounding tissues due to increased pressure
- Lymph = within lymph vessels
- Plasma = in blood
Structure and function of lymph
- S = clear tissue fluid that has been collected by the lymphatic system
- F = transport fats and proteins, transport lymphocytes, transport of pathogens to L/N
Functions of tissue fluid
- To supply cells with a stable environment
- To provide tissues with nutrients e.g. O2
Function of plasma
- Transport nutrients and wastes around the body via the blood
- Absorb/give off heat e.g. evaporation (sweat) for thermoregulation)
State 4 ways in which lymph moves through the lymphatic system
- One-way valves in lymphatic vessels prevent backflow of lymph and promote unidirectional flow
- Skeletal muscle contractions and relaxations (milking action) push lymph through
- Changes in thoracic pressure during inspiration and expiration (respiratory system)
- Smooth muscle lining vessel walls contracts and relaxes to push lymph through > peristalsis
State the pathway of fluid through the lymphatic system
- Excess tissue fluid is collected from venules, capillaries and arterioles by lymph capillaries
- Lymph transported through afferent vessel to L/N where it is filtered, lymph exits L/N via efferent vessel
- Clean lymph returned to CV system via thoracic duct
Describe 4 features of lymph capillaries and how they allow them to achieve their function
- Thin walls > can easily collect excess tissue fluid from CV system
- Overlapping epithelial cells which creates gaps > allows tissue fluid to move into capillary and prevents backflow out of capillary
- Interlaced with venules, arterioles, CV capillaries > easy access to collect tissue fluid
- Closed at one end > creates open circulatory system
Describe 2 features of lymph vessels and how they allow them to achieve their function
- Valves prevent backflow of lymph out of vessel
- Larger lumen than capillaries > allows them to transport lymph from capillaries to ducts
Function of the right lymphatic duct
Drains lymph from: the right arm and the right halves of the thorax, head and neck
Describe the structure and function of lymph nodes
- S = small clusters of specialised 2ndary lymphoid tissue that contain large amounts of leukocytes, located along lymph vessels
- F = filter lymph fluid by destroying and removing foreign particles (e.g. pathogens/dead cells) before it is returned to the CV system