lymphatic system Flashcards

(39 cards)

1
Q

Function of the Lymphatic System

A
  1. Drain excess interstitial fluid
    - returns to the blood stream and maintains blood volume
  2. Transport dietary lipids
  3. Carry out immune responses
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2
Q

How to lymphatic capillaries differ from blood capillaries

A
  • greater permeability
    larger in diameter
  • closed at one end
  • allow fluid in but not out
  • close proximity to blood capillaries
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3
Q

What do the one way swinging doors on lymph capillaries do

A
  • if pressure surrounding the vessel is higher it opens allowing fluid in until pressure is equal
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4
Q

What is a lacteal

A

specialized lymphatic capillaries that absorb fat

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5
Q

What are lympatic vessels

A
  • resemble small veins with thin walls and more valves
  • along the vessels are lymph nodes
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6
Q

What are lymphatic trunks

A

as lymph vessels exit nodes they join to form trunks
- Lumbar 2
- Intestinal 1
- Bronchomedial 2
- Subclavian 2
- Jugular 2

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7
Q

What does the Lumbar Trunk get lymph from

A
  • lower limbs
  • pelvis
  • kidneys
  • adrenal glands
  • abdominal wall
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8
Q

What does the subclavian trunk get lymph from

A
  • upper limbs
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9
Q

Where do lymphatic trunks drain into

A
  • right and thoracic ducts
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10
Q

What is the thoracic duct & where does it start

A
  • L2 (cisterna chyli)
  • 3 trunks empty right there
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11
Q

Where does the thoracic duct drain into

A
  • venous blood at the junction of left internal jugular veins and subclavian veins
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12
Q

What drains into thoracic duct

A
  • R/L lumbar
  • intestinal
  • L jugular
  • L subclavian
  • L bronchomediastinal
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13
Q

What drains into right lymphatic duct

A
  • R jugular
  • R subclavian
  • R Bronchomediastinal
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14
Q

Where does right lymphatic duct drain into

A
  • Right internal jugular vein and subclavian
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15
Q

How does thoracic duct get through diaphragm

A
  • aortic hiatus
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17
Q

How is lymph formed

A
  • excess fluid thats filtered by blood capillaries than reabsorbed
  • 3L/day
  • return any protiens that may have been lost by blood
18
Q

Decribe the flow of lymph and mechanisms used

A
  • Skeletal muscle pump
  • Respiratory pump
  • more valves than veins
  • no assistance from heart thus takes lymph hours to circulate
19
Q

2 types Immune Response of the lymphatic system

A
  1. Primary lymphatic organs
  2. Secondary lymphatic organs
20
Q

Primary Lymphatic Organs

A
  • stem cells divide and become competent
    1. Red bone marrow (B lymphocytes and pre T- lymphocytes)
    2. Thymus - pre T lymphocytes migrate to thymus to become immunocompetent
21
Q

where is the Thymus

A
  • mediastinum between aorta and heart
22
Q

What functions does the thymus have

A
  • endocrine and lymphatic function
23
Q

Secondary Lymphatic Organs

A
  • sites where immune response occurs
  • Lymph nodes
  • Spleen
  • Lymphatic Nodules and follicles
24
Q

Function of Lymph nodes

A
  • act as filters
  • trap macrophages trap and destroy foreign bodies
  • lymphocytes destroy others by immune response
  • lymph passes through many filters before the returning to the blood
25
6 Places Nodes are located in the body
- Cervical - Axillary - Thoracic - Abdominal - Pelvic - Inguinal
26
Lymphatic Function of the Spleen
- Initiates immune response by T & B cells - removes abnormal blood cells
27
Where are Lymphatic nodules
- MALT: mucosa associated lymphatic tissue - Peyers patches (ileum) - Tonsils
28
2 Types of Immunity
1. Innate (non- specific 2. Adaptive (specific)
29
Describe Innate Immunity | Lines of defense
1st Line of defense - intact skin - mucous membranes 2nd Line of Defense - Natural Killer cells - Phagocytes - Inflammation - Fever
30
Function of Natural Killer Cells
- 5-10% of lymphocytes - red bone marrow, spleen, lymphnodes - kill infected cells, tumour cells, viruses, abdomal cells - do not need prior exposure or activation (recognize abnormalities and kill them)
31
Function of Phagocytes
1. Neutrophils 2. Macrophages - ingest microbes or cell debris - forms pus - result of most inflammatory responses
32
Function of Inflammation
- non specific response to tissue damage - pain, redness - cause increased blood flow
33
Inflammatory Response
- vasodilation and increased blood flow - emigration of phagocytes from the blood to interstitial fluid - tissue repair
34
Fever Response
- abnormally high temperature - results from viral infection or inflammation - creates inhabitable environment for microbes - speeds up body reactions that aid in repair
35
What is adaptive immunity
body's ability to defend against specific viruses and toxins - involves B/T lymphocytes
36
What is anything recognized that is foreign to the body
Antigen
37
How do vaccines help immune response
- antigens are pretreated to trigger an immune response but not significant illness
38
B Lymphocytes
produced in bone marrow B lymphocytes produce antibodies ** - attack specific antigens
39
T Lymphocytes
- precursors are produced in bone marrow - Helper T cells - Cytotoxic T cells - kill infected cells, tumour cells, viruses or abnormal cells - memory T cells