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HDM Midterm - Brett > Lymphoid Tissue > Flashcards

Flashcards in Lymphoid Tissue Deck (46):
1

What makes a lymphoid organ primary ?

When it produces lymphocytes

2

What are the two primary lymphoid organs

Thymus and red bone marrow

3

What are secondary lymphocytes?

Diffuse lymphoid tissue where lymphocytes are activated in response to antigens

4

__________________ cells are most common where the body meets the outside world

Non-encapuslated

5

Non-encapsulated diffuse tissue is found where?

GI tract, genitourinary tract, respiratory passages

6

What is the difference between primary and secondary nodules

Primary nodules are dark in the middle and have a high concentration of naive cells; secondary nodules have a germinal center which is a much paler color and forms a corona

7

What area are non-stratified squamous cells found in?

Mouth, anus, vagina, respiratory tract

8

How are germinal centers different than mantles?

Germinal center is pale while the mantle is more dense

9

Where do memory cells collect in secondary nodules?

Mantle

10

What cell type is not found in the germinal center?

T cells

11

What is one example of non-encapsulated lymphoid tissue aggregates?

The tonsils

12

From most distal to most proximal what are the order of the tonsils?

Pharyngeal, palatine, lingual

13

What do the tonsils do?

They protected against inhaled or ingested substances

14

What tonsil section is characterized by large number of stratified squamous cells and 10-20 deep tonsillar crypts?

Palatine

15

Which two sections of tonsils are most similar?

Lingual and palatine. They both have crypts, stratified squamous epithelium

16

What tonsils have pseudostratified columnar ciliated epithelium?

Phayngeal

17

What does MALT stand for? Where is it found?

Mucosa-associated lymphoid tissue
It is in the GI, respiratory airways, and urinary tract

18

Where is GALT found? What does it stand for?

Gut-associated lymphoid tissue

It is found in the SI particularly the ileum, and it is characterized bu abundance of villi

19

What are peyers patches associated with?

GALT

20

The appendix is similar to what?

The peyer’s patches

21

What are the primary lymph organs?

Thymus and red bone marrow

22

The thymus is a bilobed structure in the

Mediastinum

23

When does involution occur and what is it

The process of decreased thymus activity as it becomes filled with adipose tissue

Until puberty

24

The thymus is made of lobes called ________

Septa

25

The darker staining region in the thymus is the ______ __________ while the lighter staining area is the the _____ _______

Outer cortex, inner medulla

26

The ___________________ is the site of t-lymphocyte maturation

Thymic

27

What cells produce the cytoreticulum?

Cortical (stellate) cells

28

What cells form the cortical compartment of the thymus

Subcapsular (squamous)

29

What is tightly packed with whorls of TECs?

Hassall’s copuscles

30

Where do cytokines that finalize maturation of T cells come from?

Hassal’s copuscles

31

Where are mature T cells found right before they enter circulation?

Medulla

32

What are 2 major functions of the spleen?

Reservoir for platelets, recycling center for erythrocytes

33

Periarteriolar lymphoid sheaths are made of what?

T cells

34

The most dense zone outside of the GC is the __________

Corona/mantle zone

35

The transition from white to red pulp is called _______________

Marginal zone

36

The red pulp is perfused and is in charge of what function?

Blood filtration and erythrocyte turn over

37

What are splenic cords? What are sinusiods?

Splenic cords are branches of the splenic artery that just dead end.

Sinusiods are barrel like structures made of stave cells that allow blood to flow through

38

What cleans up the recycled cells that are left in the spleen?

Macrophages

39

What is swelling made of?

Lymph

40

What is the function of the hilum in lymph nodes?

The exit for lymph

41

The outer cortex does what?

Receives lymph from surrounding area

42

The central medulla is responsible for what?

Collecting lymph on its way to the hilum

43

Where does blood and lymph meet in the nodes?

Cortex

44

What are the canals that allow lymph to get deeper into the lymph nodes

Tabeculae

45

The ____________ ________ is in the lymph node cortex and allows space for lymph to flow

Subcapsular sinus

46

Where are high endothelial venules found? What cell type are they?

Paracortex, simple cuboidal (allow movement of lymphocytes)