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Flashcards in Major trauma Deck (12):
1

3 systemic responses to injury?

Increased CO
increased minute ventilation
Febrile

2

What do we see happens with metabolism? Where does it go to?

Accelerated lipolysis
Accelerated proteolysis

Amino acids go to wound healing and acute phase proteins, glucose goes to major organs and wound healing

3

Pains main role during major trauma we want to avoid is?

INcreases the metabolic rate even more.
pre emptive analgesia is better than post wounding

4

Can nutritional intake prevent catabolism?

No can just limit it

5

2 tissues we lose with major trauma

Adipose and skeletal muscle

6

there is often major volume loss in the homeostatic response this stimulates what two apparatuses? Which releases what two hormones respectively?

Pressor receptors
Juxtaglomerular apparatus

ADH
Aldosterone

7

What are 3 serious consequences of underperfusion

Organ failure
Tissue deterioration
Reperfusion injury

8

How does major trauma stimulate hormone release?

Massive release of ACTH which causes subsequent release of cortisol and catecholamines

9

Catecholamines and cortisol both stimulate the production of inevitably what?

glucose
lower insulin and increase glucagon

10

What 3 factors associated with the endocrine reponse to major trauma increase the immune suppression of an animal

endocrine response directly
increased metabolic rate
decreased nutritional status

11

4 controllable factors for minimizing the effects of major trauma

Volume loss
starvation
tissue damage
infection

12

one way to minimize the stress endocrine response is to?

Pre emptive pain management, systemic analgesia or local pain control