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Flashcards in Second intention healing Deck (27):
1

The key components of second intention would healing?

Granulation
Contraction
Epithelialization

2

How do the phases of second intention wound healing differ from first intention

Same phases but a much extended duration of cellular phase

3

How does contraction occur?

Myfibroblasts produce actin and fibronectin

4

Rate of contraction on body? on limbs?

1mm/day
0.2mm/day

5

4 factors affecting the rate of contraction of the skin?

Inelasticity of skin
vascular insufficiency
fewer myofibroblasts
cytokines

6

Rate of epitheliazation on the body? the limbs?

0.2mm/day
0.09mm/day

7

3 ways to prevent exuberant granulation tissue?

Debridement
sterile dressing
pressure bandages

8

Describe bandage pholosiphy

pressure early is the best to limit wound size,
later it can be a catch 22. can slow healing once granulation tissue is present. but still offer mechanical protection

9

2 ways to manage exuberant granulation tissue once its there

sharp debridement
topical medicaments

10

big positives of topical medications? big disadvantages?

Owner friendly, control granulation tissue
slow contraction, slow epitheliazation

11

8 topical medications you can use to slow granulation tissue

Corticosteroids
white wound lotion
copper sulfate
furacin
preparation H
Amnion
Collagen preparations
Biosyst

12

8 topical medications you can use to slow granulation tissue

Corticosteroids
white wound lotion
copper sulfate
furacin
preparation H
Amnion
Collagen preparations
Biosyst

13

Drawback of corticosteroids

Slow epitheliazation

14

What is white wound lotion?

Lead acetate and zinc sulfate

15

Drawbacks of white wound lotion?(3)

Metabolic toxins
kill fibroblasts
slows epitheliazation
lead poisoning possibility

16

Drawback of copper sulfate?

Kills fibroblasts

17

What can you do to make fibroblasts more friendly

Mix with corn starch to dilute

18

What are the 2 things furacin does?

Stimulates granulation tissue production???
inhibits epitheliazation

19

What does furacin harbour?

harbours pseudomonas

20

What is preparation H

Yeast extract

21

What does preparation H do?

Stimulates production of granulation tissue
Slows contraction and epitheliazation

22

What does amnion do?

Inhibits granulation tissue
promotes epitheliazation
speeds healing
WAHOO!

23

What colours actually work?

Green - corticosteroids
purple - copper sulfate?
red - Amnion

24

What colours actually work?

Green - corticosteroids
purple - copper sulfate?
red - Amnion

25

collagen preparations affective?

No no hurt no benefit

26

What is in procine small intestinal submucosa? Promotes/

Collagen, proteoglycans, cytokines
Scaffold, healing modifier

27

Are split thickness skin grafts useful?

Yes inhibit granulation and promote wound contraction