Male & Female Health: Benign Prostatic Hyperplasia (BPH) Flashcards

1
Q

Signs and symptoms of BPH

A

Hesitancy, intermittent urine flow, strain or weak stream
urinary urgency and leaking/dribbling
urinary frequency, especially at night
incomplete emptying of bladder

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2
Q

5 alpha-reductase inhibitors should not be used in..

A

men who have bladder outlet obstruction symptoms without prostate enlargement

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3
Q

5 alpha-reductase inhibitor works by…

A

reducing prostate size

take awhile to work

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4
Q

1st line treatment for BPH?

A

alpha-1 blockers

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5
Q

Alpha-1 blockers mechanism

A

cause relaxation of smooth muscle in the prostate and bladder neck

reduces bladder outlet obstruction and improve urinary flow

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6
Q

Non-selective vs selective alpha blockers

A

Non-selective = more side effects = terazosin, doxazosin
selective = tamsulosin, alfuzosin, silodosin

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7
Q

If cataract surgery is planned, then txm with alpha blockers should be…

A

delayed, risk of developing intraoperative floppy iris syndrome

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8
Q

Alpha blocker warnings

A

Orthostatic hypotension/syncope
intraoperative floppy iris syndrome (IFIS)

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9
Q

Alpha blocker side effects

A

dizziness
fatigue
headache
abnormal ejaculation

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10
Q

When are non-selective alpha blockers given

A

usually at bedtime

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11
Q

5- alpha reductase inhibitors

A

Finasteride
Dutasteride

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12
Q

5 alpha reductase inhibitor CI

A

women of child bearing potential
pregnancy
children

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13
Q

5 alpha reductase inhibitor side effects

A

impotence
dec libido
ejaculation issues
breast enlargement and tenderness
sexual SE decrease over time in some men

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14
Q

5 alpha reductase inhibitor notes

A

pregnant women shouldn’t handle or take these

treatment for 6 months+ may be req for maximal efficacy

will shrink prostate and decrease PSA lvls

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15
Q
A
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