Pulmonary Conditions & Tobacco cessation: COPD Flashcards
people with what deficiency are at higher risk of developing COPD?
AAT = alpha 1 antitrypsin deficiency
Post-bronchodilator FEV1/FVC of what confirms COPD?
< 0.70
GOLD system COPD
stages 1-4
used to assess prognosis and disease progession
GOLD 1
Mild
FEV1 > 80%
GOLD 2
Moderate
50% - 80% FEV
GOLD 3
Severe
30% - 50% FEV
GOLD 4
Very severe
< 30% FEV
Most common scoring systems for COPD
mMRC
CAT
What is COPD exacerbation
increase in respiratory symptoms that worsen over < 14 days
How many exacerbations per year are considered frequent?
2
ICS is recommended in patients with,….
Eosinophil count > 300
and history of exacerbations
ICS is not recommended in patients with
Eosinophil count < 100
CAT score > 10, mMRC > 2 then…
group B
CAT score < 10, mMRC < 0-1 then….
Group A
> 2 moderate exacerbations or > 1 leading to hospitalization then…
Group E
Group A initial treatment
Bronchodilator
SAMA PRN, SABA PRN, LAMA or LABA
Group B initial treatment
LAMA + LABA
Group E initial treatment
LAMA + LABA
+ ICS if eosinophils > 300
When should antibiotics be used?
if increased sputum purulence, volume or dyspnea, or if on technical ventilation
SAMA (short acting muscarinic antagonists) drugs
Ipratropium = Atrovent
SAMA & LAMA side effects
Dry mouth
Cough
Bitter Taste
SAMA & LAMA warnings
caution in pts with narrow angle glaucoma, myasthenia graves, urinary retention, mph and bladder neck obstruction
LAMA (long muascarinic antagonists) drugs
Tiotropium = Spiriva
umeclidinium = incruse ellipta
LABA can be used as mono therapy in which disease state?
COPD