Pulmonary Conditions & Tobacco cessation: COPD Flashcards

1
Q

people with what deficiency are at higher risk of developing COPD?

A

AAT = alpha 1 antitrypsin deficiency

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2
Q

Post-bronchodilator FEV1/FVC of what confirms COPD?

A

< 0.70

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3
Q

GOLD system COPD

A

stages 1-4

used to assess prognosis and disease progession

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4
Q

GOLD 1

A

Mild
FEV1 > 80%

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5
Q

GOLD 2

A

Moderate
50% - 80% FEV

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6
Q

GOLD 3

A

Severe
30% - 50% FEV

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7
Q

GOLD 4

A

Very severe
< 30% FEV

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8
Q

Most common scoring systems for COPD

A

mMRC
CAT

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9
Q

What is COPD exacerbation

A

increase in respiratory symptoms that worsen over < 14 days

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10
Q

How many exacerbations per year are considered frequent?

A

2

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11
Q

ICS is recommended in patients with,….

A

Eosinophil count > 300
and history of exacerbations

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12
Q

ICS is not recommended in patients with

A

Eosinophil count < 100

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13
Q

CAT score > 10, mMRC > 2 then…

A

group B

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14
Q

CAT score < 10, mMRC < 0-1 then….

A

Group A

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15
Q

> 2 moderate exacerbations or > 1 leading to hospitalization then…

A

Group E

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16
Q

Group A initial treatment

A

Bronchodilator

SAMA PRN, SABA PRN, LAMA or LABA

17
Q

Group B initial treatment

A

LAMA + LABA

18
Q

Group E initial treatment

A

LAMA + LABA

+ ICS if eosinophils > 300

19
Q

When should antibiotics be used?

A

if increased sputum purulence, volume or dyspnea, or if on technical ventilation

20
Q

SAMA (short acting muscarinic antagonists) drugs

A

Ipratropium = Atrovent

21
Q

SAMA & LAMA side effects

A

Dry mouth
Cough
Bitter Taste

22
Q

SAMA & LAMA warnings

A

caution in pts with narrow angle glaucoma, myasthenia graves, urinary retention, mph and bladder neck obstruction

23
Q

LAMA (long muascarinic antagonists) drugs

A

Tiotropium = Spiriva
umeclidinium = incruse ellipta

24
Q

LABA can be used as mono therapy in which disease state?

25
For ICS containing LABA, it is important to
rinse mouth after use to prevent candidiasis
26
Roflumilast CI
moderate to severe liver impairment
27
Roflumilast side effects
Diarrhea weight los nausea dec appetite insomnia HA
28