Male Infertility Flashcards
(56 cards)
what, at gonadal level, indicates that you will become female?
absence of a Y chromosome
name the 2 primitive genital tracts?
wolffian duct
mullerian duct
what 2 chemicals cause the development of the male internal genital tract?
testosterone
mullerian inhibiting factor
what do the wolffian ducts form?
male genital tract
what do the mullerian ducts form?
female genital tract
when is the earliest time on a scan that you can tell if its a male or female?
16 weeks
patient presents with amenorrhoea and lack of pubic hair in puberty…
suspect androgen insensitivity syndrome
what is androgen insensitivity syndrome?
congenital insensitivity to androgens
what is the karyotype in androgen insensitivity syndrome?
46XY
inheritance of androgen insensitivity syndrome?
x linked recessive
what happens to the testes in androgen insensitivity syndrome?
testes develop but dont descend
when do the testes descend into the scrotal sac?
before birth
why is it important that testes descend?
need a lower temp outside body to facilate spermatogenesis
what muscle facilitates the descent of the testes?
dartos
what should be done with testes at birth?
checked to see that 2 are present and if they arent they should be found on a scan and child should have surgery before puberty
what is cryptorchidism?
undescended testest
male will usually remain fertile in unilateral cryptorchidism T or F
T
Tx of cryptorchidism and why?
orchidopexy before age 14
orchidectomy
risk of cancer
what structures are responsible for spermatogenesis?
seminiferous tubules
what structures are responsible for testosterone production?
leydig cells
when are LH and FSH made in men?
constantly
what does FSH do in men?
tells sertoli cells to make testosterone
sertoli cells secrete….
seminiferous tubule fluid
androgen binding globulin
inhibin and activin
what do inhibin and activin do?
regulate FSH secretion and controls spermatogenesis
