Mannitol

Question 1

Mannitol trade name

Answer 1

Osmitrol

Question 2

Mannitol class

Answer 2

Osmotic diuretic

Question 3

Mannitol MOA

Answer 3

Increased osmotic pressure in the intravascular space to promote water movement from the interstitial space to the vascular space.

Question 4

Mannitol Indications

Answer 4

Cerebral Edema

Question 5

Mannitol Contraindications

Answer 5

Hypotension
Pulmonary edema
Severe dehydration
Intracranial bleeding

Question 6

Mannitol side effects

Answer 6

Pulmonary edema
Dehydration
Seizures
Confusion
Tachycardia
Headache
Chest pain
Hypertension
Hypotension
Nausea/ vomiting

Question 7

Mannitol Dose

Answer 7

Adult 0.5-1.0 g/kg IV/IO over 5-10 minutes
Ped same as adult

Question 8

Mannitol onset/ duration

Answer 8

Onset 1-3 hours diuresis/ 15 min for ICP
Duration 4-6 hours diuresis/ 3-8 hours ICP