Flashcards in Microbiology of the Genital tract Deck (77)
What is the predominate bacteria in the normal vaginal flora and what does it do?
lactobacillus spp. - produces lactic acid and hydrogen peroxide to suppress the growth of other bacteria
What other organisms are present in the normal vaginal flora?
Group B-haemolytic Strep
Name 3 non-sexually transmitted genital tract infections
Bacterial vaginosis (fishy smell)
What % of woman are colonised by Candida but show no symptoms of a thrush infection?
What are predisposing factors for a candida infection?
recent antibiotic therapy
High oestrogen levels (pregnancy, some contraceptives)
Poorly controlled diabetes
What is the presentation of thrush?
Intensely itchy white vaginal discharge
How do you clinically diagnose thrush?
High vaginal swab for culture
What organism causes most cases of thrush?
What is the treatment of Candida infections?
Topical clotrimazole pessary or cream
What organisms can cause Bacterial vaginosis?
Others include anaerobes
What are the predisposing factors of Bacterial vaginosis?
What are the symptoms of bacterial vaginosis?
Thin, watery, fishy smelling vaginal discharge
How do you diagnose bacterial vaginosis?
Raised vaginal pH >4.5
What is looked for in a laboratory sample of suspected bacterial vaginosis?
What scoring system estimates the proportion of clue cells to epithelial cells and lactobacilli?
Hay-lyson scoring system
What is the treatment for bacterial vaginosis?
What are the 3 classifications of Prostatitis?
1. Acute bacterial prostatitis
2. Chronic bacterial prostatitis
3. Chronic prostatitis / chronic pelvic pain syndrome (CP/CPPS)
What are the organisms involved with acute bacterial prostatitis?
Same as a UTI, E.coli and other coliforms, enterococcus sp.
Always check for STI's
What is acute bacterial prostatitis?
A rare complication of a UTI in men
What are the symptoms of acute bacterial prostatitis?
Symptoms of a UTI, may have lower abdo/back/perineal/penile pain
Tender prostate on examination
How is acute bacterial prostatitis diagnosed?
MSSU for C&S
tests for STI's
What is the treatment for acute bacterial prostatitis?
Ciprofloxacin for 28 days
Trimethoprim for 28 days if high C.diff risk
Name 3 bacterial STI's
Treponema pallidum (Syphilis)
Name 3 viral STI's
Human papilloma virus (genital warts)
Herpes simplex virus (Genital herpes)
Hepatitis and HIV
Name 3 parasitic STI's
Phthirus pubis (Pubic lice/crabs)
What parts of the body does Chlamydia effect?
Describe Chlamydia trachomatis
Obligate intracellular bacteria with biphasic life cycle - "energy parasite"
What colour does Chlamydia trachomatis stain with gram stain?
It doesn't, no peptidoglycan in the cell wall
What are the 3 serological groupingsof Chlamydia trachomatis?
Serovars A-C = Trachoma (eye infection) (no an STI)
Serovars D-K = Genital infection
Serovars L1-L3 = Lymphogranuloma venereum