Preterm Infant Flashcards

1
Q

What is Preterm?

A

Birth before 37 weeks gestation

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2
Q

What is Term?

A

Birth between 37 and 42 weeks gestation

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3
Q

What is Post term?

A

Birth after 42 weeks gestation?

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4
Q

What are risk factors for child death?

A
Maternal age
Smoking
Disadvantaged circumstances
Preterm delivery
Low Birth weight
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5
Q

What age is the most common for child death?

A

Birth to 1 year

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6
Q

What are risk factors for preterm delivery?

A

> 2 preterm deliveries in the past
Abnormally shaped uterus
Multiple pregnancies
<6 month interval between pregnancies
In vitro fertilisation
Smoking, drug taking, alcohol during pregnancy
Poor nutrition and diabetes, High BP etc.

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7
Q

What problems do preterm babies have?

A
Get colder quicker
More fragile lungs
Don't breathe well
Fewer reserves
Pulse oximetry often indicated
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8
Q

What should be done while waiting for placental transfusion?

A

Keep the baby warm

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9
Q

How do you keep the baby warm effectively?

A

Keep baby in a plastic bag under a radiant heater.

Do immediately, even while the baby is still wet

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10
Q

Why is the baby having fragile lungs an issue?

A

Over-inflation causes damage leading to inflammation and long term morbidity
- Bronchopulmonary dysplasia

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11
Q

What are common concerns in preterm infants?

A
Temp control
feeding/Nutrition
Sepsis
System immaturity/dysfunction
Other e.g. metabolic, Retinopathy of prematurity
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12
Q

Give 4 examples of System immaturity/Dysfunction?

A

Resp distress syndrome (RDS)
Patent ductus arteriosus (PDA)
Intraventricular haemorrhage (IVH)
Necrotising enterocolitis

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13
Q

Why is hypothermia very very bad in infants?

A

Is an independent risk factor for neonatal death

Increases severity of all pattern morbidities

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14
Q

Give 4 reasons why thermal regulation may be ineffective?

A

Low BMR
Minimal muscular activity
Subcut fat insulation is negligible
High ratio of surface area to body mass

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15
Q

Name 4 ways a baby can be kept warm?

A

Wrap or bags
Skin to skin care
Transwarmer mattress
Prewarmed incubator

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16
Q

Why would an preterm baby have growth and nutrition issues?

A

Limited nutrient reserves
Immature metabolic pathways
Increased nutrient demands

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17
Q

How long should gestational correction be used for a baby born at 32-36 weeks gestation?

A

1 year

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18
Q

How long should gestational correction be used for a baby born before 32 weeks?

A

2 years

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19
Q

What could cause Early Onset Neonatal Sepsis?

A

Mainly bacteria acquired before and during delivery

20
Q

What could cause Late Onset Neonatal Sepsis?

A

Acquired after delivery, usually nosocomial or community sources

21
Q

What organisms can cause neonatal sepsis?

A

Group B strep (GBS)
Gram -ve organisms (Klebsiella, E.coli, Pseudomonas, Salmonella)
Gram =ve (Staph aureus, Coagulase -ve staphylococci (CONS), Strep pneumoniae, Strep pyogenes)

22
Q

What 5 things are good managements of infection?

A
Prevention
Hand washing
Super vigilant and infection screening
Judicial use of ABx
Optimum supportive measures
23
Q

What is important to know about incubators?

A

Incubators Increase Infection

24
Q

Name 3 respiratory complications of prematurity?

A

RDS
Apnoea of prematurity
Bronchopulmonary dysplasia

25
What disease is assoc. with Hyaline Membrane Disease?
RDS
26
What is primary pathology Hyaline membrane disease?
Surfactant deficiency/immaturity
27
What is secondary pathology hyaline membrane disease?
Alveolar damage Formation of exudate from leaky capillaries Repair
28
Is hylaine membrane disease common?
75% of infants born before week 29 | 10% born after 32 weeks
29
What are clinical features of RDS?
``` Tachypnoea Grunting Intercostal recessions Nasal flaring Cyanosis Worsen over minutes to hours ```
30
In RDS, when is Nadir?
Day 2-4
31
What is the management of RDS?
Maternal steroid to help with surfactant production in the fetus Ventilation (Invasive vs non-invasive)
32
Name 2 cardiovascular concerns in preterm infants
Patent ductus arteriosus | Systemic hypotension
33
What duct problem can occur in pretermers?
Duct doesn't respond to "close" signals
34
In IVH in pretermers, where does the bleeding begin?
Into the germinal matrix
35
How many germinal matrix haemorrhage (GMH) lead to an IVH?
80%
36
When is the insult of an IVH present by?
72 hours
37
What can help prevent an IVH?
Antenatal steroids Prompt and appropriate resuscitation Avoid haemodynamic instability
38
What should be avoided to help prevent an IVH?
Hypoxia Hypercarbia Hyperoxia Hypocarbia
39
What happens in a Grade 1 and 2 IVH?
Neurodevelopment delay in up to 20% | 10% mortality
40
What happens in a Grade 3 and 4 IVH?
Neurodevelopmental delay in up to 80% | 50% mortality
41
What is the most common neonatal surgical emergency?
Necrotising Enterocolitis (NEC)
42
What is NEC?
Necrosis across small and large intestine
43
What is the clinical picture of NEC?
Usually after recovering from RDS Early signs = lethargy and gatric residuals Bloody stool, temp instability, apnoea and bradycardia
44
What are other complications of prematurity?
Retinopathy of prematurity (Usually 6-8 wks after delivery) Early = hypoglycaemia and hyponatraemia Late = Osteopenia of prematurity
45
Can being born prematurely have an effect on the infants adult life?
Yes - Insulin resistance, hypertension, vascular changes,