MISSED NEURO/EYE Flashcards

(91 cards)

1
Q

where is serotonin produced?

A

raphe nucleus

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2
Q

sysnthesis of GABA?

A

nucleus accumbens

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3
Q

lack o fGABA is implicated in the cause of

A

HD

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4
Q

what part of the brain plays a role in cognition, motivation, orgasm, and drug addiction?

A

Ventral tegmentum.

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5
Q

Principal site of norepinephrine production?

A

locus ceruleus

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6
Q

what would you see on CSF of MS?

A

oligoclonal IgG bands

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7
Q

when would you see increased opening pressure on lumbar puncure?

A

Hydrocephalus, Subarachnoid hemorrhage or infection like bacterial meningitis

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8
Q

High opening pressure, high protein, low glucose, very high WBC and mostly neutrophils, organisms on gram stain . What meningitis?

A

Bacterial Meningitis

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9
Q

Normal opening pressure, clear appearance, slightly high protein, normal glucose, high WBC, mostly lymphocytes. What meningitis?

A

Viral Meningitis

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10
Q

Normal to increased opening pressure, turbid or viscous appearance, very high protein, low glucose, very high WBC, mostly lymphocytes. Positive Ziehl-Neelsen stain. What meningitis?

A

Fungal/TB meningitis

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11
Q

Elevated Opening pressure, yellow to red blood stained appearance, high protein, normal glucose, normal WBC?

A

Subarachnoid Hemorrhage

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12
Q

oligoclonal bands, IgG, myelin basic protein

A

MS

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13
Q

myelin forming cells, CNS (brain + spinal cord)

A

Oligodendrocytes

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14
Q

where are oligodendrocytes derived from

A

neuroectoderm

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15
Q

Where is microglia derived from

A

mesoderm

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16
Q

Where are schwann cells derived from?

A

Neural crest

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17
Q

myelin forming cells, PNS

A

Schwann Cells

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18
Q

what glial cells form ROS

A

Microglia

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19
Q

What reflexes are absent in Conus medullaris?

A

Achilles S1

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20
Q

What reflexes are absent in cauda equina?

A

Patellar (L4) and Achilles (S1)

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21
Q

Distribution of cauda equina?

A

Unilateral

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22
Q

Distribution of conus medularis

A

bilateral

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23
Q

transverse myelitis think

A

conus medullaris

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24
Q

lumbar radiculopathy think

A

cauda equina

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25
UMN with conus or cauda?
Conus
26
LMN with conus or Cauda?
LMN
27
hindbrain derived from
rhombencephalon
28
midbrain derived from
mesocephalon
29
forebrain derived from the
prosencephalon
30
Paresis of muscles of mastication, coupled with jaw deviation suggests
trigeminal nerve damage
31
With Brown Sequard Syndrome pain and temp present
contralaterally 1-2 levels below the lesion
32
With brown sequard syndrome, proprioception, vibration, fine touch sensation are
ipsilateral below the lesion or at lesion
33
Sleepwalking waves
delta
34
Night terror waves
Delta
35
Narcolepsy occurs during
REM
36
Awake stage of sleep waves
Beta, NE and Ach active
37
awake, eyes closed waves
alpha
38
light sleep N1 waves
Theta, hypnic jerks
39
45-55% of sleep and bruxism (teeth grinding) occurs here
N2.
40
What waves do you see in N2
Theta + Sleep spindles, K complexes
41
What waves do you see in N3 sleep
Deepest sleep --> Delta waves. Sleep walking occurs here
42
what stage does sleepwalking, night terrors and enuresis occur?
N3
43
REM waves
Beta (like awake)
44
when does dreaming and memory consolidation, atonia and erections occur?
REM.
45
Tx for insomnia; avoid in narcolepsy
Suvorexant
46
Good for night terrors, sleepwalking tx
Benzodiazepines
47
Less hangover, less tolerance, short acting and decreases REM
Zolpidem/Zaleplon
48
Promotes wakefulness, 1st line tx for narcolepsy
Modafinil
49
Neurotransmitter that initiates sleep
Serotonin (raphe nucleus)
50
Promotes dreaming neurotransmitter
acetylcholine
51
decreased in REM
Norepinephrine
52
promotes NREM
GABA
53
Promotes wakefulness but decreased in narcolepsy
Orexin
54
Promotes wakefulness
dopamine
55
what stage does Enuresis occur (bedwetting)
N3
56
Tx for Enuresis
Eneuresis alarm --> detects urine. wakes kid up. Desmopressin (1st line med) Imipramine (2nd Line)
57
LSD receptor
5-HT2A Serotonin
58
PCP receptor
NMDA
59
Cocaine + meth receptors
Alpha and beta adrenergic
60
Heroin receptor
mu opoid
61
Cannabinoids receptor
(marijuana) CB1 + CB2
62
Nicotine receptor
Nicotinic acetylcholine receptor
63
Benzodiazapenes/barb receptors
GABA
64
Arnold chiari malformations have abnormalities at the
spinomedullary junction
65
slow tremor when pointing or extending towards an object
Intention tremor
66
high frequency tremor with a sustained posture. Tremor is worsened with movement and/or anxiety
Essential tremor - tx: nonselective beta blockers, primidone
67
Dysarthria, dysphagia, ataxia --> stroke artery?
PICA. Lateral medullary syndrome (wallenburg)
68
ipsilateral face hemiparesis + ipsilateral deafness, what artery for stroke?
AICA --> lateral pontine syndrome
69
Alcohol may improve a. __ tremor
Essential
70
Doesn't have tremor at rest but trying to grab object and get tremor.
Intention tremor --> seen in MS / chronic alcoholism --> can be called cerebellum tremor. Tx benzotropine
71
How to tx essential tremor?
Propranolol + primidone
72
yawning.. drug?
opioids
73
excessively thirsty, drug?
MDMA (ecstasy)
74
Pinpoint pupils shown in, drug?
Opioid intox or stimulant withdrawal
75
Dental carries, drug?
meth mouth
76
bugs crawling on skin
cocaine intox
77
conjuctival injection (red eyes), in what drug?
marijuana, cannibinoids
78
hallucinations, bruxism, euphoria, altered sense of time
MDMA (ectasy)
79
patient is extremely aggressive/violent, what drug did they take?
PCP.
80
what is most associated with PCP?
Rotational torsional nystagmus
81
PCP is an NMDA receptor ___
antagonist
82
is meth a depressant or stimulant
stimulant
83
what drug may cause renal tubular necrosis and rhabdomyolysis
cocaine.
84
hepatitis, abscesses, HIV/AIDS, right sided endocardiditis (roth spots, janeway lesions, splinter hem, osler nodes, valve vegetations) associated with what drug?
Opioids
85
life threatening: agitation, confusion, fever, tachycardia, hallucinations, death from alcohol withdrawal is called ___ and at what time?
delirium tremens and 48-72 hours
86
tremors, anxiety GI upset from alcohol withdrawal occurs
6-12 hours
87
Hallucinations from alcohol withdrawal occurs
12-24 hours
88
Seizures (tonic clonic) from alcohol occurs
24-48 hours
89
how to tx alcohol withdrawal?
Benzos: Long acting diazepam
90
Wernicke Korsakoff Syndrome is associated with what vitamin
B1
91