Mod 2 Hematopoietic Function Flashcards
(98 cards)
1
Q
Process of forming blood
A
Hematopoiesis
2
Q
liquid protein
A
plasma
3
Q
White blood cells
A
Leukocytes
4
Q
Red blood cells:
Hemoglobin
Hematocrit
A
Erythrocytes
5
Q
Oxygen carrying component
A
Hemoglobin
6
Q
amount of blood volume occupied by erythrocytes
RBC is 45% plasma 55%
A
hematocrit

7
Q
Platelets
A
Rambo states 
8
Q
Smallest blood vessels
A
Capillaries
9
Q
Blood is a___
A
Solution
10
Q
Plasma is an example of what___it is made mostly of water
A
Solvent
11
Q
The following are examples of what? Red blood cells, platelets, macro and micro nutrients, white blood cells, and hormones.
A
solutes
12
Q
What is normal pH of blood or tissues?
A
7.35-7.45
13
Q
A
Hemostasis
14
Q
stages of hemostasis with a cut
- Vessel spasm helps decrease loss of blood.
- Vessel stops the spasm.
3.
- Brings healthy tissue together.
- Macrophages eat debris infection in fibroblasts form new fibers.
A
- formation of platelet plug.
- Blood coagulation.
- Clot retraction.
- Clot dissolution.
15
Q
Clotting Casade
Prothrombin >___>fibrinogen>turns into___>____
A
thrombin
Fibrin
Platelets
16
Q
What is active within the clotting cascade?
A
Fibrin and thrombin
17
Q
what is non-active in the clotting cascade
A
Fibrinogen and prothrombin
18
Q
A
D
19
Q
what is decrease levels of white blood cells
A
LEUKOPENIA
Usually disease process and immunotherapy
20
Q
increase levels of white blood cells
A
leukocytosis
21
Q
Key players in the inflammatory response and in fighting infections
Normal range 5000 to 10,000
A
Leukocytes
22
Q
never let monkeys eat bananas
What does the stand for?
A
neutrophils
lymphocyte
monocyte
EOSINOPHIL
Basophils
23
Q
no nucleus
Transfer oxygen and carbon dioxide
A
Red blood cells
24
Q
Phagocytizes bacteria
A
Neutrophils
25
Phagocytize antigen-antibody complexes, attack parasites
Eosinophils
26
release histamine during inflammation vasodilation)
Basophil
27
Phagocytizes bacteria, dead cells, and cellular debris
Monocytes
28
One cell thick
Capillary
29
usually the first to arrive at the site of infection
* fight bacteria infection
Neutrophil
30
Neutropenia
31
Fever, tired, chills
Neutropenia
32
Bacterial
33
viral
Will cure itself eventually
Infectious mononucleosis
34
Infectious mononucleosis
35
Affects B cells
36
Lymphoma
37
less aggressive
Hodgkin’s lymphoma
38
Hodgkin’s lymphoma
The lymphoma cells are in *one lymph node group*or one part of the tissue or an organ
Stage one
39
Hodgkins lymphoma
The lymphoma cells are in at least two lymph nodes groups on the same side of the diaphragm, or the lymphoma cells are in one part of a tissue or an organ and the lymph nodes near that organ
* above the diaphragm
Stage two
40
Hodgkins lymphoma
The lymphoma cells are in lymph nodes above and below the diaphragm. Lymphoma cells may be found in one part of a tissue or an organ near these lymph node groups. Cells may also be found in the spleen.
* above and below the diaphragm
Stage three
41
Hodgkins lymphoma
Cells are found in several parts of one or more organs or tissues, or the lymphoma cells are in an organ and in distant lymph nodes.
* has spread
Stage four
42
The disease returns after treatment
Recurrent
43
Presence of Reed Sternberg cells in a lymph node biopsy
Hodgkins lymphoma
44
C
45
It tends to spread more = poor prognosis
non-Hodgkin’s lymphoma
46
Visual
lymphoid -create T&B cells naturally
Killer cells -kill off infections agents
Myeloid- everything else
47
Create immature, white blood cells
Leukemia
48
Acute lymphoblastic leukemia
49
Acute myeloid leukemia
50
Slow moving
Affects primarily adults
Responds poorly to therapy, yet most patients live many years after diagnosis
chronic lymphoid leukemia
51
52
affect primarily adult adults
Respond poorly to chemotherapy, but the prognosis is improved with allogeneic bone marrow transplant
Chronic myeloid leukemia
53
Leukemia
54
affects the cells that turn into plasma cells
Dark spots on x-ray
Multiple myeloma
55
Multiple myeloma
56
D
57
Carry oxygen to tissues with glucose = energy
Red blood cells
58
production of erythrocytes (RBC)
Regulated by erythropoietin from kidney
Occurs in bone marrow
erythropoiesis
59
Anemia
60
Iron deficiency anemia
61
Made of four sub protein’s, main one is iron
Hgb
62
Iron deficiency anemia
Too much iron is toxic to the liver
63
Storage form of iron
Serum ferritin
64
Help absorb iron frol GI tract
Transferrin saturation
65
bilateral numbness and tingling
Low levels of energy
Unsteady gate
Pernicious anemia
66
Pernicious anemia
67
affect all blood cells (RBC, WBC, platelets)
Aplastic anemia
68
Aplastic anemia
69
False
70
Hemolytic anemia
71
sickle cell anemia
72
heterozygous
Less than half of the erythrocytes are sickled
Sickle cell trait
73
homozygous
Most severe
Almost all erythrocytes are sickled
Sickle cell disease
74
manifestations:
typically appear around four months of age where stars clothes
Sickle cell anemia
75
painful episodes that can last for hours days
pain caused by tissue ischemia and necrosis
Triggered by dehydration, stress, high altitudes, and fever
Sickle cell anemia
76
genetic
creation of hemoglobin is abnormal
Unable to carry oxygen
Thalassemia
77
Thalassemia
78
Iron deficiency anemia
pale red blood cells
79
Sickle cell anemia
80
Pernicious anemia
larger red blood cells and irregular shaped
Megablastic (larger)
81
Polycythemia
-clotting
82
Polycythemia
83
increase levels of platelets
Thrombocytosis
84
decrease levels of platelets
Thrombocytopenia
85
Hemophilia a
86
Von Willebrand’s disease
87
Von Willebrand disease type one
88
Von Willebrand disease type two
89
Von Willebrand disease type two
90
follows autosomal recessive
No measurable, von Willebrand factor or factor vIII
Causes severe bleeding problems
Von Willebrand disease type three
91
occurs with Wilms, tumor, genital, heart, disease, systemic lupus erythematosus, and hypothyroidism
Acquired type von Willebrand’s disease
92
Von Willebrand disease
93
B
94
Clot, plot, clot > excessive bleeding
Malfunction of the vascular system causes excessive bleeding
Disseminated intervascular coagulation
95
complications: shock and multisystem organ failure due to a lack of blood supply
Diagnosis : CBC and bleeding studies
Treatment: identify and treat underlying cause
Disseminated intervascular coagulation
96
To Little coagulation
idiopathic thrombocytopenia purpura
97
unable to breakdown clots due to lack of enzyme
One Willebrand‘s factor comes in causes a clot > enzyme, breaks up the clots
Hypercoagulation deplete platelet levels > causes clots> uses platelets> decreases platelets= bleeding
Not genetic a side effect of something else
Thrombotic thrombocytopenic purpura
98
False
