Flashcards in Module 18- Blood Disorder part 2 Deck (58):
What is the most common genetic disorder of the blood?
Sickle Cell Disease
Sickle Cell Disease is a ________ form of hemolytic anemia?
What ethnicities are primarily affected by sickle cell disease?
What test is done to see if you are a sickle cell carrier?
Signs and symptoms of sickle cell disease start appearing within the first ______mo with ____ and _____ observed?
Sickle cell disease is due to ______ hemoglobin
In sickle cell disease fluid ______ results and blood _____ occurs?
Due to blood viscosity and blood stasis _____ and ______ can result?
A hematocrit score for a sicle cell pt. can range between ____ and ___%
Normal life span of RBC?
Life span of a sickle cell RBC?
Which form of sickle cell disease do children and adolescence have?
Sickle Cell Crisis
What do we as clinicians do if someone experiences a sickle cell crisis?
call med services
What is the major organ affected in sickle cell disease?
What procedure may provide a cure for young patients with symptomatic sickle cell disease?
allogeneic stem-cell transplant
What do sickle cell pts. take daily until age 6 to prevent infection
You could use a chemotherapy med called ___ to increase ______ thereby decreasing the permanent formation of sickle cells?
There is a decreased ______ and an increased _____ seen radiographically with Sickle Cell Disease?
Sickle Cell Disease can present radiographically as a _____ trabecular pattern appearing as "____ _____" rows with large _____ spaces?
Sickle Cell pts. will have a generalized ______ of the oral tissues?
______ ______ of the mouth can lead to a sickle cell crisis
Do we use epi in LA on sickle cell pts.?
Can we use nitrous on sickle cell pts?
yes with oxygen greater than 50%
What does polycythemia mean?
increase in number and concentration of RBC above normal
Hemoglobin and Hematocrit are increased to more than ____% in polycythemias?
What are the 3 general categories of polycythemia?
In relative polycythemia we loose ____ which leads to a corresponding loss of ____
What can cause relative polycythemia (fluid loss)
In relative polycythemia the ______ of cells increases due to?
loss of plasma level
Which polycythemia is an actual increase in RBC count and hemoglobin value?
Polycythemia Vera (primary polycythemia)
What else is elevated in polycythemia vera?
Blood viscosity ________ in polycythemia vera?
Polycythemia Vera is a _____ condition resulting from a _____ disorder in which _____ RBC's proliferate?
The tongue, mucous membranes, and gingiva are what color in polycythemia vera?
What is the treatment for polycythemia vera?
Pts should avoid ____ supplements and ____ medications with a history of polycythemia vera?
Secondary polycythemia is also called ____
What patients can have a secondary polycythemia?
A decrease in the total number of WBC's is termed a?
What are the 2 conditions that can lead to leukopenia?
Disease/intoxification of bone marrow
What is a rare, serious disease involving the destruction of bone marrow
What is the term for a malignant neutropenia?
What is the most extreme abnormal cause of leukocytosis?
What is often administered to a patient with lymphocytopenia?
Bleeding disorders can be due to platelet _____ or ______
Where are the clotting factors produced?
What is the oldest known hereditary bleeding disorder?
What hemophilia is "Classic Hemophilia"
Hemophilia A is caused by a reduction in the amount/function of factor?
What % of people with hemophilia have type A?
Hemophilia B is also called " _____ _____"
Hemophilia B is a deficiency of factor _____
Both hemophilia A and B are ___ linked ___ genetic diseases?
What disease is characterized by a prolonged bleeding time in the presence of a normal platelet count?
Von Willebrand's Disease
Patients with Von Willebrands have a defect in platelet ___ and the ______ pathway?
Extraoral signs of Von Willebrands include?
petechiae of skin
What does Hemarthroses mean?
bleeding into soft tissue of joints