Epinephrine
nonselective (alpha and beta)
Epinephrine: Actions
- increases vasoconstriction
- promotes bronchodilation
Epinephrine: Uses (3)
treat anaphylaxis, bronchospasms, and cardiogenic shock
Epinephrine: Onset and peak
rapid
Epinephrine: Side effects (8)
- nausea, vomiting
- dizziness, headache
- agitation, restlessness
- hyper/hypo glycemia
Epinephrine: Adverse effects (4)
- palpiltations, tachycardia
- pumonary edema
- dyspnea
Epinephrine: Drug interactions
- beta blockers dec epinephrine action
- digoxin causes cardiac dysrhythmia
Atenolol
selective beta1 antagonist
Atenolol: Actions
decreases HR and BP
Atenolol: Uses (3)
treat hypertension, angina (chest pain), and acute MI (heart attack)
Atenolol: Onset and peak
PO onset = 1 hr
peaks in 2-4 hrs
Atenolol: Side effects (3)
- depression
- dizziness
- ED
Atenolol: Adverse reactions (3)
- brady/tachy cardia
- hypotension
- life threatening: bronchospasm
Atenolol: Drug interactions (3)
- inc absorption with anticholingenics
- dec effect with non-steroidal anti-inflammatory drugs
- inc risk of low blood glucose
Bethanechol
cholinergic; direct-acting parasympathomimetic
Bethanechol chloride: Action
contraction of bladder
Bethanechol chloride: Uses (2)
treats non-obstructive urinary retention and neurogenic bladder
Bethanechol chloride: Onset and peak
PO onset = 0.5-1.5 hrs
peaks 1-2 hrs
Bethanechol chloride: Side effects (3)
- hypotension
- inc salivation
- N/V/D
Bethanechol chloride: Adverse effects (2)
- bronchospasm
- wheezing
Bethanechol chloride: Contraindications (3)
- bradycardia
- asthma
- urinary tract obstruction
Bethanechol chloride: Teaching (2)
- monitor for overdose
- orthostatic hypotension
Atropine
cholinergic antagonist; parasympatholytic
Atropine: Action (3)
- inc HR
- pupil dilation
- dec GI motility
