Module 4 Flashcards
(70 cards)
What affects communicable disease transmission? (3)
- Social Factors (1)
- Living conditions (1)
- Climate (1)
Human barriers of pathogens? (6)
- Acidic stomach (1)
- Physical barrier of skin (1)
- Mucus produced by goblet cells
waft pathogens to stomach (1) - Inflammation causes area to
vasodilate and white blood cells
to arrive quickly (1) - Expulsive responses such as
sneezing and coughing (1) - Intestines and skin covered in
harmless bacteria to compete
with harmful pathogens (1)
Plant physical defenses? (3)
- Waxy cuticle provides physical
barrier on leaf surface (1) - Cell wall barrier beneath waxy
cuticle (1) - Callose makes it harder for
pathogens to enter cells (1)
Plant chemical defenses? (2)
- Produce antibiotic compounds
to inhibit growth of bacteria or
fungi (1) - Produce insecticides to reduce
infection of plant viruses
caused by vectors (1)
What is the immune response when antigens are detected? (4)
- Phagocytosis (1)
- T lymphocyte activation (1)
- B lymphocyte activation (1)
- Antibody production by plasma
cells (1)
What are the steps of phagocytosis? (5)
- Phagocytes receptors bind to
pathogens antigens (1) - Pathogen engulfs into vesicle
phagosome (1) - Lysosome fuses with
phagosome to form
phagolysosome (1) - Pathogen removed from
phagocyte by exocytosis (1) - Some antigen molecules left,
with the phagocyte now being
an antigen-presenting cell (APC)
(1)
What are T lymphocytes? (3)
- White blood cells with receptors on
their surface (1) - Binds to complementary antigens
(1) - Once they bind, clonal expansion
will occur through mitosis to form
specific T cells (1)
What are the types of T cells? (4)
- T helper cells (1)
- T killer cells (1)
- T regulatory cells (1)
- T memory cells (1)
What are the roles of T helper and T killer cells? (2)
- T helper cells release chemicals to
activate B lymphocytes (1) - T killer cells destroys any infected
cells (1)
What are the role of T regulatory and T memory cells? (2)
- T regulatory cells suppress other
immune cells and prevent damage
to host cells (1) - T memory cells remain in the
bloodstream in case of reinfection
and can divide into the other T cells
(1)
How are B cells activated? (2)
- When cytokines/interleukins are released from T
helper cells (1) - When antibodies on their surface
binds to complementary antigens (1)
What do B cells differentiate into when activated? (4)
- Plasma cells (1)
- Produces antibodies
complimentary to the antigen (1)
- Produces antibodies
- Memory cells (1)
- Remains in the bloodstream and
will divide into plasma cells if
antigens are present again (1)
- Remains in the bloodstream and
Describe the antibody structure? (3)
- Quaternary structure (1)
- Four polypeptide chains (2 heavy
and 2 light chains) (1) - Held by disulfide bridges (1)
What is meant by the variable and constant region? (4)
- Variable region is the top half of the
antibody that is unique (1) - Where the antigen binding site is
located (1) - Constant region is the bottom half
that stays the same (1) - Binding site for immune system
cells such as B cells and phagocytes
(1)
What is meant by hinge region? (2)
- Region between constant and
variable region (1) - Provides antibody with stability (1)
What are the ways antibodies destroy pathogens? (3)
- Agglutination (1)
- Anti-toxins (1)
- Opsonisation (1)
How does agglutination work? (3)
- Antibodies contain 2 antigen
binding sites (1) - Binds and clumps 2 pathogens
(1) - Phagocytes can engulf multiple
pathogens at the same time (1)
How do neutralizing toxins work? (2)
- Antibodies bind with toxin (1)
- Antibody toxin complex is
destroyed by phagocyte (1)
How do opsonins work? (1)
- They bind and tag to foreign cells to make them easier for
phagocyte recognition (1)
What is primary immune response? (2)
- When you are infected with a
certain pathogen for the first time
(1) - Causes production of memory
T and B cells (1)
Why is primary immune response slow? (2)
- Takes time for the correct B
cells to be activated (1) - And for them to divide into
plasma cells to produce
antibodies (1)
Why is secondary immune response so fast with no symptoms? (3)
- T and B memory cells will
recognize the antigen (1) - T memory cells divide into T
killer cells (1) - B memory cells divide into
plasma cells to produce
antibodies (1)
What is active immunity? (2)
- Making your own antibodies
stimulated by an antigen (1) - Can be natural from illness or
artificial from vaccination (1)
What is passive immunity? (2)
- Given ready made antibodies
produced from another
organism (1) - Can be natural from breastfed
milk or artificial from injection
(1)