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Felder 3rd semester > Module 5 Musculoskeletal > Flashcards

Module 5 Musculoskeletal Flashcards

(82 cards)

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1
Q

Opiates and Opioids are used for what level of arthritis

A

Moderate to Severe arthritis

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2
Q

Inhibits prostaglandin synthesis, cyclooxygenase, arachidonic conversion

A

Salicylates

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3
Q

Aspirin is an example of a

A

Salicylates

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4
Q

arachidonic conversion + cyclooxygenase =

A

Prostaglandin

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5
Q

Where do Salicylates come from

A

bark of willow tree

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6
Q

Avg dose of Aspirin is

A

81mg-650mg

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7
Q

What is the max dose for Aspirin as an anti-inflammatory and what is it used for

A

3g/day Arthritis

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8
Q

What is the max dose for Aspirin as an Non-narcotic analgesic and what is it used for

A

650mg 1 4-6 hrs Moderate mild pain

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9
Q

What is the max dose for Aspirin as an Antipyretic

A

650mg q 4 hrs

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10
Q

What is the max dose for Aspirin as an Antiplatelet

A

81mg or 325mg / day

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11
Q

Viral infection causes fatty liver

A

Reyes Syndrome

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12
Q

Acute poisoning in Salicylates can lead to

A

Rhabdomyolysis, acute renal failure

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13
Q

If poisoning occurs in Salicylates what can we use to absorb substances

A

Activated charcoal

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14
Q

A non-Salicylates is also called

A

NSAIDS

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15
Q

Ibuprofen max dose is (for arthritis)

A

1200mg-2400mg q 4-6 hrs

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16
Q

Ibuprofen max dose for pain is

A

400-800mg q 4-6 hrs

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17
Q

Naproxen max dose is

A

500-1000mg / day

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18
Q

How should Indocin be administered

A

50-200 mg/day in 2-3 doses

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19
Q

Diclofenac should be administered

A

100-200 mg/day

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20
Q

Misoprostol is a combination drug that includes

A

Cytotec

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21
Q

Celecoxib is used to treat

A

Osteoarthritis and Rheumatoid arthritis

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22
Q

What is the max dose for Acetaminophen

A

4 grams a day

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23
Q

What is the max dose for Acetaminophen for a patient with ETOH

A

2 grams a day

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24
Q

Drug used to lower the effects of Acetaminophen

A

Mucomyst

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25
If meds are +10days for Acetaminophen what should patient do
consult prescriber
26
What should we monitor for a patient taking DMARDS
Blood sedimentation rate
27
Gold salts are used in
Chrysotherapy
28
Chrysotherapy is used to
Decrease tenderness, swelling, pain
29
How long should it take for full therapeutic effect in Chrysotherapy
6 months
30
Auranofin is a drug used in .... and can only be given
Chrysotherapy .. PO LARGE MUSCLE MASS
31
If protein gets in blood during Chrysotherapy what should be done
d/c tx.
32
4 side effects of Chrysotherapy
Stomatitis loose stools Bone marrow suppression Bluish green skin discoloration
33
We should report any use of gold salts prior to what test
TB test
34
Chrysotherapy causes what type of reaction
Nitroid reaction
35
Cytokine produced by macrophages, results in inflammation and cartilage erosion
Tumor Necrosis Factor
36
Decreases immune system response, used for psoriasis and arthritis
TNF inhibitors
37
4 side effects of TNF inhibitors
Leukemia Lymphoma Hepatitis B infection TB
38
Etanercept, Adalimumab, and Golimumab are examples of what kind of drug class
TNF inhibitor
39
How do we infuse TNF inhibitors
over 2 hours, 2 weeks - 6 - 8
40
Penicillamine should be taken how ... and not with what
on an empty stomach ... not with antacids
41
Chelator med
Penicillamine
42
How long does it take to see improvement with Methotrexate
3-6 weeks
43
Triple therapy with Methotrexate includes what other 2 drugs
Hydroxychloroquine and sulfasalazine
44
Hydroxychloroquine can be toxic to
eyes
45
sulfasalazine should be given how
With food, Full glass of water
46
Sulfasalazine can cause (2)
Male infertility | yellow orange skin discoloration
47
Patients with gout should decrease foods that contain
Purine
48
Uric acid in gout should be what #
less than 6mg/dl
49
Used to treat/prevent acute flares of gout
Colchicine
50
When should we d/c Colchicine
when patient reaches 8mg
51
In gout patient can use what uric acid inhbitor
Allopurinol
52
Allopurinol can also be called a
Hypouricemic
53
4 side effects of Allopurinol
alopecia SJS purpuric rash Bone marrow supression
54
This drug is used to enhance uric acid excretion
Probenecid
55
Probenecid can also be called a
Uricosuric
56
How should we give Probenecid
With food OR antacid
57
What is the action of a Bisphosphonate
Increases bone density
58
How should we give Bisphosphonates
Full glass of water on empty stomach.
59
What is something a person should not do after taking a Bisphosphonate
Do not lay down for 30 minutes
60
What are 3 side effects of Bisphosphonates
Esophageal Ulcerations Bone pain Headache
61
What is something a person should not consume if taking Bisphosphonates
Milk
62
Alendronate, Risedronate, Zoledronic Acid, and Ibandronate are examples of what drug class
Bisphosphonates
63
Raloxifene is an example of what drug
Selective Estrogen Receptor Modulator (SERM)
64
Selective Estrogen Receptor Modulator (SERM) drugs are used for
Bone, Uterine cancer
65
Forteo (Teriparatide) is what kind of drug
Bone Formation Agent
66
Forteo contributes what hormone and what can it cause
Contributes parathyroid hormone and can cause hypercalcemia
67
What is the major adverse effect of Central Acting drugs
Drowsiness, Dizziness, Ataxia
68
Define Ataxia
inability to control muscle
69
Inhibits skeletal muscle contraction by blocking conduction within the spinal cord
Central Acting drugs
70
Muscle spams, epilepsy, electrolyte imbalance can all be treated with what drug group
Central Acting drugs
71
Central Acting drugs should be given
With food
72
Titrate means
Start slow, gradually increase
73
Taper means
Decrease slowly
74
Methocarbamol a central acting drug can cause what
Greenish, Brownish, Black, urine discoloration
75
Neuromuscular blockers are different from central acting drugs because
Acts on receptor site, peripheral acting
76
interrupts transmission at skeletal neuromuscular junction
Neuromuscular blockers
77
Agonist Depolarizing Neuromuscular blockers, differ from Competitive Non Depolarizing Neuromuscular blockers because
Competitive Non Depolarizing Neuromuscular blockers REQUIRE MED TO REVERSE ACTIVITY
78
Muscle spasms require Peripheral or Central
Peripheral
79
It is important to tell patient that Neuromuscular blockers
Have no effect on pain or consciousness
80
Dantrolene is an example of a
Direct Acting drug
81
A major adverse effect of Dantrolene is
Malignant hyperthermia
82
Skeletal muscle stimulants can cause (2)
increase in saliva | increase in sweat

Felder 3rd semester (10 decks)

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