module 5 reds Flashcards

1
Q

what is cell signalling

A

chemicals bind to glycoprotein receptors to cause a direct response or or a cascade of events

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2
Q

describe the structure of a hepatocyte

A

large nucleus, prominent golgi, lots of mitochondria

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3
Q

what are kupffer cells

A

macrophages of the liver- ingest foreign pathogens

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4
Q

what are the three functions of the liver

A

carbohydrate metabolism, deamination of excess amino acids, detoxification

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5
Q

how does the liver control glucose levels

A

hepatocytes convert glucose to glycogen, and glycogen to glucose

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6
Q

how does the liver deaminate amino acids

A

remove amino group and turn it into ammonia then urea to go to the kidney (ornithine cycle)

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7
Q

how does the liver detoxify the body

A

catalase in hepatocytes breaks down hydrogen peroxide into oxygen and water

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8
Q

describe the action of adh

A

-adh released from pit gland and binds to receptors on membrane
-triggers formation of camp as second messenger
-vesicles in collecting duct fuse with membranes on outside of the cell in contact with medulla
-aquaporins inserted to make membrane permeable to water
-water moves out of cells into tissue fluid of medulla and blood capillaries

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9
Q

how is glomerular filtration rate measured

A

measure of creatinine (breakdown prod of muscles)

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10
Q

what does high glomerular filtration rate mean

A

kidneys are not working properly because there is damage to the sieves

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11
Q

structure of a sensory neurone

A

one dendron, one axon

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12
Q

structure of a relay neurone

A

many short axons and dendrons

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13
Q

structure of a motor neurone

A

many short dendrites, one long axon

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14
Q

describe the events leading to the secretion of insulin

A

-glucose phosphorylated to produce atp
-atp closes k+ channels so k+ builds up
-ca2+ channels open and ca2+ diffuses in
-results in movement of vesicles to membrane

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15
Q

describe how glucagon is involved in the regulation of blood glucose concentration

A

-glucagon released from alpha cells in islets of langerhans
-promotes conversion of glycogen to glucose (glycogenolysis)
-negative feedback reduces secretion of glucose
-glucagon inhibits insulin secretion

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16
Q

explain the symptoms of adrenal failure

A

glucocorticoids regulate carb metabolism, lack of mineralocorticoids causes low blood pressure, salt cravings

17
Q

functions of adrenaline

A

inc heart rate, inc blood glucose, inc blood flow to muscles, pupils dilate

18
Q

functions of noradrenaline

A

increases heart rate, increases blood pressure, widens pupils

19
Q

functions of androgens

A

reg of sex characteristics and cell growth

20
Q

functions of cortisol

A

reg of metabolism

21
Q

examples of commercial use of auxin

A

rooting powders, micropropagation, weed killers, promotes fruit ripening

22
Q

which hormones are thought to be involved in control of leaf drop

A

auxin and ethene

23
Q

roles of gibberellins

A

increase in internodal length, seed germination, prevents leaf abcission, aids stomatal opening, promotes fruit development

24
Q

describe the fight or flight response

A

when a threat is detected by the ans, the hypothalamus communicates with the sns and the adrenal cortical system. adrenocorticotropic hormone released from pit gland which stimulates the adrenal cortex to release adrenaline etc

25
action of adrenaline
adrenaline binds to receptor and triggers activation of adenylyl cyclase, which triggers the conversion of atp to cyclic adenosine monophosphate, phosphorylating other enzymes
26
why does a lack of atp lead to muscle rigidity
atp required to detach myosin head from actin so myosin remains attached, so muscle stays contracted
27
why is glucose required for the contraction of skeletal muscle
glucose as resp substrate for atp synthesis. atp needed to break cross bridges between myosin and actin- atp hydrolysed to adp and pi to reset myosin heads