MRI Flashcards

1
Q

What are the stages of hemorrhage graded on MRI? What length of time does each stage represent?

Intracranial hemorrhage: principles of CT and MRI interpretation. Eur Radiol (2001)

A
Hyperacute: first few hours
Acute: 1-3days
Early subacute: 3-7 days
Late subacute: 7-14 days up to 1m
Chronic: 1 months - years
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2
Q

What are the four types of magnetic behavior/susceptibility?

Intracranial hemorrhage: principles of CT and MRI interpretation. Eur Radiol (2001)

A

Diamagnetic
Paramagnetic
Supraparamagnetic
Ferromagnetic

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3
Q

What is diamagnetic?

Give an example

A

A type of magnetic behavior.
Substances without unpaired electrons. Without magnetic field - dipole moment is zero. With magnetic field - small negative suscpetibility (takes away from field strength).
Ex: oxy-hemoglobin. Carbon (diamond, graphite), water, bismuth

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4
Q

What is paramagnetic?

Give an example

A

A type of magnetic behavior
Substances with unpaired electrons. Without magnetic field - dipoles cancel each other out. With magnetic field - align in direction of the magnet and moments add together - positively effects magnetic field.
Ex: deoxy and methemoglobin, gadolinium, tungsten, cesium, aluminum, sodium

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5
Q

What is superparamagnetic?

Give an example

A

Substances with large #’s of unpaired electrons. Intermediate positive magnetic susceptibility
Example: hemosiderin, iron oxide contrast agents

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6
Q

What is ferromagnetism?

A

Half filled electron shells.
Strong attraction and alignment (projectiles across room). Will retain magnetization after removal from the magnetic field. –> permanent magnet

Examples: iron, steel, gadolinium in native state

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7
Q

What is classified as hyperacute hemorrhage? What will it appear as on T1 and T2 weighted images? Why?

A

Hyperacute - Within 24 hours

T1: Iso to hypointense - oxyhemoglobin - acts as fluid
T2: hyperintense - acts as fluid

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8
Q

What is classified as acute hemorrhage?

How will acute hemorrhage appear on T1 and T2 sequences?

What stage of hemoglobin breakdown is occurring?

A

Acute - 1-3 days
T1: Iso to hypointense
T2: hypointense

Deoxyhemoglobin

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9
Q

What is classified as early subacute hemorrhage?

What will early subacute hemorrhage appear on T1 and T2 images?

What stage of hemoglobin breakdown is occurring?

A

Early subacute 3-7 days

T1: Hyperintense
T2: Hypointense

Hemoglobin: Methemoglobin (intracellular)

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10
Q

What is classified as late subacute hemorrhage?

What will late subacute hemorrhage appear on T1 and T2 images?

What stage of hemoglobin breakdown is occurring?

A

Late subacute: 7-14d (up to 1m)

T1: Hyperintense
T2: Hyperintense

Hemoglobin: Met-hemoglobin (extracellular from red cell lysis)

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11
Q

Which sequence is important in differentiation between acute and early subacute hemorrhage?

Why?

A

T1

Acute: iso to hypointense
Early subacute: hyperintense
late subacute: hyperintense

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12
Q

What sequence is important in differentiation between early and late subacute hemorrhage?

Why?

A

T2

Early subacute: Hypointense
Late subacute: Hyperintense - increased extracellular fluid

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13
Q

What is classified as chronic hemorrhage?

What will late chronic hemorrhage appear on T1 and T2 images?

What stage of hemoglobin breakdown is occurring?

A

Chronic: >1 month

T1: Hypointense
T2: Hypointense

Hemoglobin: hemosiderin and ferriting - crystalline storage forms of iron

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14
Q

What is the equation of the magic angle artifact?

A

When 3 cos^2(angle)-1 = 0

54.74 (55)

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15
Q

How can the magic angle artifact be avoided?

A

Using longer TE times (most common in

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16
Q

Why does the magic angle artifact occur?

A

The angel at which the dipolar interaction between two nuclei is zero.
Dipole-dipole interactions will result in loss of T2 magnetization and loss of signal within a signal. Without interactions -signal will be increased.