MSK Pathology - OA

Question 1

OA aetiology ?

Answer 1

Degenerative wear and tear

Question 2

Pathogenesis of OA ?

Answer 2

1. Cartilage Hydration Decreases with Age
2. 􏰁Less Resistant to Friction􏰁
3. Cartilage Erosion 􏰂
4. 􏰁Exposure of Bone􏰁
5. Grinding􏰁
6. Mechanical Damage &Inflammation

Question 3

Morphology of OA ?

Answer 3

1. Eburnation of bone
2. Cartilage degeneration
3. Peripheral O-phytes

Question 4

Clinical features of OA ?

Answer 4

1. 40 years old<
2. Large, weight bearing joints
3. Pain worse with activity and better with rest
4. Crepitus
5. Bony overgrowths (O-phytes)

Question 5

What are nodules called in PIP and DIP ?

Answer 5

PIP - Bouchards

DIP - Heberton

Question 6

OA diagnosis ?

Answer 6

Normal blood-work

Imaging - narrow joint spaces, ankylosis and various deformity

Question 7

OA surgery ?

Answer 7

Joint replacement / Spinal fusion