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Flashcards in Mucosal immunity Deck (3)
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1

Physical barriers in mucosal immunity

The intestinal mucosa provides a semi-permeable barrier made up of compacted glycoproteins, anti-microbial peptides and secretory IgA

2

Innate immunity in the mucosa

Dendritic cells, macrophages and ILCs are located close to the epithelium

They are attracted to the intestinal mucosa by the chemokine MIP3a

Dendritic cells reach past tight junctions to sample the intestinal lumen

3

Adaptive immunity in the mucosa

IgA, Th17 and Treg cells are notably found in the mucosa

Peyer's patches are lymphoid aggregates in the small intestine