Flashcards in Musculoskeletal Diseases Deck (33):
Calcitonin is secreted by the ____.
_____ decreases bone resorption by suppressing osteoclast activity.
Parathyroid hormone regulates blood level of ___.
How does parathyroid hormone influence blood levels of Ca?
osteoclastic activity to release CA form bone’
resorption of Ca from kidney
resorption of phosphate
Peak bone mass occurs at ages __-__.
The degree of bone mineralization is called:
increased resorption of bone due to inc. osteoclastic activity occurs at ages __-__.
Rapid decrease in bone mass occurs with menopause. __% per year for 5 years initially, and __% later.
Too little bone
Too little bone mass
Too little bone mineralization
What is the biggest reason alcoholism leads to bony changes?
malabsorption of nutrients
Osteoporosis risk factors
caucasian/asian > african american
What is a T-score?
normal value for a young adult female
What is a Z score?
value for your age range
What is the T score classification for osteopenia?
-1 to -2.5 SD from average
What is the T score classification for osteoporosis?
-2.5 or more SD from average
When do you begin to see changes on Xray?
> 30% bone mass lost
Senile osteoporosis age and gender incidence:
men = women
Clinical features of senile osteoporosis?
dowagers hump, exaggerated rib, pubic rami fx
Intervention/prevention Ca recommendations:
adults > 50 yrs 1200
adults < 50 yrs 1000 mg
*dairy, green, veggies
Intervention/prevention D3 recommendations:
adults > 50 yrs 800-1000
adults < 50 yrs 400-800
*egg yolks, fortified milk, saltwater fish
fosamaz, actonel, boniva, reclast
Osteoporosis medication examples:
PT considerations for osteoporosis?
Bracing to resist flexion (post vertebral fx)
Which fractures are most likely in osteoporosis?
Childhood osteomalacia is known as:
What is a looser zone?
wide linear lucent in the cortex of a long bone
(finding in osteomalacia.. at risk for fx)
Paget disease age and gender incidence:
male = female
Paget disease is characterized by:
unorganized bony formation that can lead to:
thickened skull, tibial bowing, nerve compression, varus deformity, flexed posture
Biggest issue for children with osteomalacia:
affects endochondral growth plates
Biggest issue for adults with osteomalacia:
Ca does not get deposited in new bone