Myocardial Infarction Meds

Question 1

Epinephrine

Answer 1

Treats Cardiac Arrest
C: General Beta AR agonist
MA: Increases activity of the SA node, inducing myocardial contractions

Question 2

Isoproterenol

Answer 2

Treats Cardiac Arrest
C: General Beta AR agonist
MA: Increases activity of the SA node, inducing myocardial contractions

Question 3

Propranolol

Answer 3

Reduces spread of necrosis
C: Beta 1 AR Antagonist
MA: Blocks the fight or flight response in the heart, reducing HR, CO, and anoxia
Also reduces activity of the RAAS

Question 4

Tissue plasminogen activator (tPA)

Answer 4

Reduces spread of necrosis
C: Clot Buster
MA: Sleep up the conversion of plasminogen to plasmin causing fibrolysis to occur premature, causing blood clots to dissolve quickly

Question 5

Streptokinase

Answer 5

Reduces spread of necrosis
C: Clot Buster
MA: Sleep up the conversion of plasminogen to plasmin causing fibrolysis to occur premature, causing blood clots to dissolve quickly

Question 6

Urokinase

Answer 6

Reduces spread of necrosis
C: Clot Buster
MA: Sleep up the conversion of plasminogen to plasmin causing fibrolysis to occur premature, causing blood clots to dissolve quickly

Question 7

Lidocaine

Answer 7

Treat Cardiac dysrhythmias
C: Sodium Channel Blocker
MA: Suppresses the formation of action potentials associated with an ectopic foci
Drug causes action potentials to reach threshold less frequently, longer refractory period- allows SA node to recatch electrical current

Question 8

Diuretics

Answer 8

Treat Cardiac Failure

first line treatment, used to treat fluid overload

Question 9

Spironolactone

Answer 9

Treat Cardiac Failure
C: Aldosterone receptor antagonists
MA: reduce symptoms of edema and block aldosterone’s role in promoting cardiac remodeling

Question 10

Metroprolol

Answer 10

Treat Cardiac Failure
C: Beta-adrenergic receptor antagonists
MA: reduce sympathetic stress on a failing heart

Question 11

Digoxin

Answer 11

Treat Cardiac Failure
C: Cardiac glycosides
MA: Produce a positive inotropic effect on the myocardium; this effect increases cardiac output that helps to maintain tissue perfusion

Question 12

LCZ696

Answer 12

Treats Cardiac Failure
Combo of: Neprilysin inhibitor, sacubitril with an angiotensin II receptor blocker
More effective in preventing cardiac failure

Question 13

Neprilysin

Answer 13

an enzyme that breaks down (metabolizes) natriuretic peptides like atrial natriuretic peptide

Question 14

Sacubitril

Answer 14

Inhibits neprilysin

The accumulation of ANPs which reduce salt and water retention associated with heart failure.