Treat Hyperlipidemias

Question 1

Lovastatin

Answer 1

HMG coenzyme A reductase
Inhibits the enzyme leading to suppresion of lipoprotein synthesis (component of cholesterol) blocking ENDOGENOUS cholesterol formation

Question 2

Gemfibrozil

Answer 2

Hepatic triglyceride inhibitor
Inhibits trigylecerids synthesis in the liver (building block of cholesterol), suppressing lipoprotein syntheses- decreasing LDLs and increasing HDLs that activates the reverse cholesterol transport from PVB (carries chol to liver for destruction)

Question 3

Ezetimibe

Answer 3

Cholesterol Transport protein inhibitor
Blocks absorption of dietary cholesterol and cholesterol that enters enterohepatic circulation- targets EXOGENOUS source of cholesterol