Preventing Secondary Blood Clots

Question 1

Aspirin

Answer 1

Thrombolytic drug
COX inhibitor
Prevents platelet plug formation by preventing TXA, a signal that notifies platelets to collect together- reducing platelet adhesion

Question 2

Clopidogrel

Answer 2

Thrombolytic drug
ADP antagonist
Prevents platelet plug formation by inhibiting ADP receptors on platelets, preventing chemical signal from stimulating platelet aggregation

Question 3

Warfarin

Answer 3

Anticoagulant
Vitamin K antagonist
Inhibits vitamin K dependant enzymes in the liver leading to the liver’s inability to create clotting factors – preventing blood clots

Question 4

Dabigatran (Pradaxa)

Answer 4

Anticoagulant
Thrombin inhibitor
Inhibits just thrombin, inhibiting activation of fibrinogen and eventually blocking blood clot formation

Question 5

Heparin

Answer 5

Anticoagulant
Antithrombin activator
Activates antithrombin that inhibits thrombin from converting to fibrin- directly inhibiting the clot cascade

Question 6

Fibrolytic drugs

Answer 6

drugs like tPA, etc. are known as “clot busters” that are used to dissolve preformed blood clots; these drugs reduce the spread of necrosis that cause tissue damage

Question 7

Antithrombic

Answer 7

drugs like aspirin, etc. reduce platelet aggregation and reduce the risk for the reoccurrence of MI’s or strokes- work fast

Question 8

Anticoagulants

Answer 8

like heparin, etc. inhibit the functions of the clotting cascade in the blood which prevents blood clot formation; treats pulmonary embolisms, deep vein thrombosis, etc