Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Neuro Week 2 > Neoplasms of CNS > Flashcards

Neoplasms of CNS Flashcards

(76 cards)

Start Studying
1
Q

what does the suffix blast indicate?

A

embryonic/undifferentiated cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what do all primary CNS cancers end with?

A

Oma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

are adult neoplasms commonly supra or infratentorial?

A

supratentorial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

are child neoplasms commonly supra or infratentorial?

A

infratentorial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

name two common grade 1 benign neoplasms of CNS

A

neurofibroma and meningioma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what does enhancement signal in CNS neopplasms?

A

disruption of the BBB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what indicates disruption of BBB in MRI?

A

contrast enhancement in T1 MRI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what is the most common childhood malignant CNS neoplasm?

A

medulloblastoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

where is medulloblastoma found?

A

in cerebellum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is histo finding with medulloblastoma?

A

homer wright rosettes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what are homer wright rosettes?

A

small blue cells found in medulloblastoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what can medullblastoma cause in ventricular system?

A

blockage of fourth ventricle…so non communicating hydrocephalus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what can medulloblastoma send to spinal cord?

A

drop metastes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what grade is pilocytic astrocytoma?

A

grade I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is cell issue in pilocytic astrocytoma?

A

low grade astrocytoma so astrocyte is issue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is most common benign childhood neoplasm?

A

pilocytic astorcytoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what does pilocytic astrocytoma stain + for?

A

GFAP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

where is pilocytic astrocytoma most often found in kids?

A

cerebellum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what are the two components of the pilocytic astrocytoma?

A

cystic portion and solid mass

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

do pilocytic astrocytoma and medulloblastoma enhance or not enhance contrast on MRI?

A

both enhance it

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

if there is a pilocytic astrocytoma in the optic nerve, what is it called?

A

optic glioma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

what is histo finding in pilocytic astrocytoma?

A

rosenthal fibers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what are rosenthal fibers?

A

eosinophilic corkscrew fibers..in pilocytic astrocytoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what are ependymomas from?

A

ependymal cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
where is ependymomas found?
4th ventricle
26
is ependymoma a good or bad prognosis?
not so great
27
what is histo finding of ependymoma?
perovascular pseudorosette
28
what is a perivascular pseudorosette?
ependymoma histo finding
29
what can ependymoma do to spinal cord?
send drop metasteses
30
what can ependymoma cause in ventricular system?
hydrocephalus
31
what is the most common type of CNS neoplasm in adult?
meningioma
32
what is most common deadly adult neoplasm of CNS?
glioblastoma
33
what is a diffuse astrocytoma?
cerebral hemisphere astrocyte neoplasm in adults
34
what age does diffuse astrocytoma effect?
adults
35
is diffuse astrocytoma enhancing?
no
36
where is diffuse astrocytoma found>
mainly cerebral hemis
37
what grade is diffuse astrocytoma?
II
38
what grade is anaplastic astrocytoma?
II
39
what is location of anaplastic astrocytoma?
cerebral hemis
40
what grade is glioblastoma?
grade IV
41
what cell type do glioblastoma come from?
astrocytes
42
where are glioblastomas found?
cerebral hemi
43
what can glioblastoma cross?
corpus callosum
44
when glioblastoma crosses corpus callosum what is it called?
butterfly glioma
45
what will glioblastoma stain + for?
GFAP
46
what is a word used to describe glioblastoma?
pseudopalasading
47
what does it mean for glioblastoma to be pseudopalasading?
central area of necrosis surrounded by outer layer of pleomorphic tumor cells
48
does glioblastoma enhance?
yes...it has enhancing ring around the tumor
49
who gets oligodendrogliomas?
adults
50
where do you get oligodendrogliomas?
cerebral hemis
51
what lobe is most common for oligodendrogliomas?
frontal lobe
52
what cell do oligodendrogliomas come from?
oligodendrocytes
53
what is histo finding in oligodendrogliomas?
fried egg cells
54
what does it mean to be fried egg cell?
round nuclei with clear cytoplasm
55
what can happen to oligodendrogliomas that is unique?
frequently have calcifications
56
what is grade of oligodendrogliomas?
II or III
57
when is oligodendrogliomas a grade III neoplasm?
if it enhances
58
are meningiomas malignant or benign?
usually benign
59
where is meningiomas?
near brain surfaces and in parasaigittal region
60
is meningioma extra or intra axial?
extra axial
61
what is cell origin for meningiomas?
arachnoid cells
62
what are two histo findings in meningiomas?
cellular whorls and calcifications
63
what is usual grade of meningiomas?
grade I
64
metasteses to brain are usually one or multiple?
multiple usually
65
name two PNS neoplasms
schwannoma and neurofibroma
66
what are four finding or neurofibromatosis type 1?
cafe au lait lisch nodules neurofibromas dermal neurofibromas in PNS
67
what cell does schwannoma come from
schwann cell origin
68
who gets schwannoma?
adults
69
where doe schwannomas usually occur?
cerebellopontine angle
70
what CNs does schwannoma involve?
CN V, VII and VIII
71
where can schwannomas be localized to?
CN VIII in internal acoustic meatus
72
if schwannoma localized to CN VIII, what is it called?
vestibular schwannoma
73
if you have bilateral vestibular schwannomas what do you prob have?
NF type 2
74
how does vestibular schwannoma present?
hearing loss and tinnitus
75
what is histo specialty of schwannoma ?
hypocellular and hypercellular areas running up next to each other
76
what is inheritance of NF 1 and NF 2?
AD

Neuro Week 2 (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions