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RENAL > [nephrotoxins+rhabdo] > Flashcards

[nephrotoxins+rhabdo] Flashcards

1
Q
A

acute tubular necrosis

interstitial nephritis

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2
Q
A

NSAIDs

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3
Q
A

Hb

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4
Q
A

myoglobin

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5
Q
A

light chains / Igs

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6
Q
A

crystals

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7
Q
A

radiocontrast material

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8
Q
A

phenytoin
lamotrigine
valproate

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9
Q
A 
Aminoglycosides
penicillins
sulfonamides
rifampicin
amphotericin
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10
Q
A

gentamicin
amikacin
streptomycin

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11
Q
A

give single bolus cf. extended regimens

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12
Q
A

pre-hydrate with 0.9% sodium chloride

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13
Q
A

urate
K+
CK
PO4 3-

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14
Q
A

AKI

Hyperkalaemia

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15
Q
A

muscle pain
muscle swelling
red/brown urine

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16
Q
A

serum CK (>1000iu/L)

17
Q
A

+ haematuria

BUT WITHOUT BLOOD ON MICROSCOPY

18
Q
A

no RBCs

Blood on dipstick

19
Q
A

MI

20
Q
A

rule out MI

21
Q
A

troponin

22
Q
A

reduced

23
Q
A

enters muscle

24
Q
A 
Hyperkalaemia Tx
\+
IV Fluid rehydration to prevent AKI
\+
Sodium bicarbonate
25
Q
A

alkalise the urine. Myoglobin to less toxic form.

26
Q
A

T

27
Q
A

DIC

RENAL (14 decks)

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