[reno-vascular/HUS/TTP] Flashcards

1
Q
A

hyper

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2
Q
A

atherosclerosis
fibromuscular dysplasia
anti-phospholipid syndrome
external compression

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3
Q
A

Raised BP resistant to Tx

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4
Q
A

worsening renal function with ACEi

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5
Q
A

bilateral renal artery stenosis

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6
Q
A

rapid onset pulmonary oedema

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7
Q
A

renal artery stenosis

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8
Q
A

affected

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9
Q
A

renal angiography

not 1st - invasive

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10
Q
A

CT/MRI

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11
Q
A

angioplasty

stents

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12
Q
A

Haemolytic uraemic syndrome

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13
Q
A

MAHA

microangiopathic haemolytic anaemia

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14
Q
A

intravascular haemolysis

RBC fragmentation

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15
Q
A

endothelial damage
thrombosis
fibrin strand deposition
haemolysis of RBCs

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16
Q
A

platelet consumption

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17
Q
A

e.coli O157

18
Q
A

verotoxin damages endothelium

19
Q
A

undercooked meats

20
Q
A

abdominal pain

bloody diarrhoea

21
Q
A

schistocytes

22
Q
A

haematuria

proteinuria

23
Q
A

normal clotting

24
Q
A

renal vasculature

25
Q
A

RRT

Plasma exchange

26
Q
A

thrombotic thrombocytopenic purpura

27
Q
A

ADAMTS13

28
Q
A

cleaving multimers of WvF

29
Q
A

aggregating large WvF proteins

30
Q
A
MAHA
AKI
CNS signs
fever
thrombocytopenia
31
Q
A

urgent plasma exchange - emergency

32
Q
A
Urine dipstick (haem, protein)
Film (schisto)
33
Q
A

30-300mg albumin/24 hours

34
Q
A

Prognosis for renal problems

35
Q
A

CVS

36
Q
A

no

37
Q
A

specialised dipstick

ACR ratio

38
Q
A

> 2.5 men

>3.5 women

39
Q
A

ACEi/ARB

always start ACE regardless of BP

40
Q
A

annually