Nervous system Flashcards
List the 3 parts of the brainstem from most superior to inferior
Midbrain
Pons
Medulla
Which part of the brainstem is just posterior to the optic chiasm?
Midbrain
Which part of the brainstem has the superior, middle and inferior cerebellar peduncles?
Pons
Which part of the brainstem has the pyramids, decussation of the pyramids and olives?
Medulla
Which two vesicles of the embryological neural tube give rise to the brainstem?
Mesencephalon - midbrain
Rhombencephalon - metencephalon (pons and cerebellum) + myelocephalon (medulla)
What parts of the ventricular system of the brain lie within the midbrain?
Cerebral aqueduct
4th ventricle
Which cranial nerves emerge from the pontomedullary junction?
Abducens (VI) + Facial (VII) + Vestibulocochlear (VIII)
Which cranial nerve that emerges from the pontomedullary junction has the longest intracranial course, and what is its clinical significance?
Abducens nerve - travels to superior orbital fissure, while all the others travels to the internal acoustic meatus
Makes it vulnerable to injury from increased intracranial pressure (convergent strabismus), though can cause false localising sign
What produces the pyramids, and what is their function?
Descending motor tracts - pyramidal tracts
What produces the decussation of the pyramids?
Where the motor fibres cross over to the contra-lateral side of the body
What produces the olives?
Neural cell bodies
What are the open and closed parts of the medulla?
Open - superior
Closed - inferior
What structure does the open part of the medulla open onto?
4th ventricle
What is the obex?
Point in human brain where 4th ventricle narrows to become central canal of the spinal cord, occurring in the caudal medulla where decussation occurs
What is the middle cerebellar peduncle made of, and what is its function?
Pontine nucleus of opposite hemisphere - connects cerebellum to pons
Which part of the brainstem has cerebral peduncles, and what are they made of?
Midbrain - contains ascending sensory fibres and descending motor fibres from the cortex, while connecting midbrain and cerebrum
Which part of the brain lies immediately superior to the midbrain?
Diencephalon (thalamus and hypothalamus)
Which part of the brain lies immediately inferior to the midbrain?
Rhombencephalon - metencephalon (pons and cerebellum) + myelocephalon (medulla)
On which part of the brainstem is the superior and inferior colliculi?
Midbrain
What projection is seen on the bottom surface of the hypothalamus?
Infundibulum/pituitary stalk
What is the name given to the midline structure connecting the two cerebellar hemispheres?
Vermis
List the lobes of the cerebellum
Anterior lobe
Posterior lobe
Flocculonodular lobe
Which part of the brain has tonsils?
Cerebellum
What part of the cerebellum lies above the foramen magnum and what is the clinical significance of this?
Cerebellar tonsils - when there is a sudden drop in intracranial pressure, the tonsils may herniate through the foramen magnum, which is referred to as “cerebellar coning”
What name is given to the large fissure separating the two cerebral hemispheres?
Median longitudinal fissure
What connects the two cerebral hemispheres?
Corpus callosum - made up of commissural fibres
What does the posterior aspect of the cerebrum lie on?
Tentorium cerebelli - covers cerebellum
In which lobe is the primary motor cortex?
Frontal lobe
In which lobe is the primary sensory cortex?
Parietal lobe
In which lobe is the primary visual cortex?
Occipital lobe
In which lobe is the primary auditory cortex?
Temporal lobe
At what vertebral level does the spinal cord terminate in adults and kids?
Adults - L1/L2
Kids - L2/L3
At what vertebral level does the dura mater terminate?
S2
At what vertebral level does the arachnoid mater terminate?
S2
What is the conus medullaris?
Tapered lower end of the spinal cord
What happens to the pia mater after the spinal cord ends?
Reaches conus medullaris and extends as a thin filament called the filum terminale and attaches to the periosteum of the coccyx to become the coccygeal ligament
At what vertebral level would you perform a lumbar puncture in adults and kids?
Adults - L3/L4
Kids - L4/L5
How many pairs of spinal nerves are there?
31 (8C, 12T, 5L, 5S, 1Co)
Is damage to the cauda equina considered an upper or lower motor neurone lesion?
Lower motor neurone lesion
From which arteries do the left and right vertebral arteries arise?
Subclavian artery
How is the basilar artery formed and with which part of the brain is it most closely related to?
Union of vertebral arteries, found near the pons/pontomedullary junction
In which groove does the anterior cerebral artery travel?
Median longitudinal fissure
In which groove does the middle cerebral artery travel?
Lateral sylvian fissure
In which groove does the posterior cerebral artery travel?
Calcarine sulcus
Describe the blood supply to the primary motor cortex
Mainly MCA, small region by ACA
Describe the blood supply to the primary sensory cortex
Mainly MCA, small region by ACA
Describe the blood supply to the primary visual cortex
PCA (calcimine branch of PCA)
Describe the blood supply to the primary auditory area of the brain
MCA
Describe the blood supply to the areas of olfaction in the brain
MCA
What system supplies blood to the posterior aspect of the circle of willis?
Vertebro-basilar system - supplies the cerebellum, thalamus and the brainstem
What commonly occurs following an aneurysm of the posterior cerebral artery?
Oculomotor palsy - CN III is found just under posterior cerebral artery and just over superior cerebellar artery. Down and out appearance of affected eye(s)
List the nerve supply components to the arteries of the brain
Carotid sinus - group of pressure receptors at junction of CCA and ICA; sensory nerves are from the glossopharyngeal nerve and the vagus nerve
Carotid body - group of chemoreceptors on posterior wall of terminal part of CCA; sensory innervation from the glossopharyngeal nerve.
Sympathetic motor nerves - from superior cervical ganglion from plexus around ICA
Describe the venous drainage of the brain
Drained by a series of veins which drain into dural venous sinuses, which are present between the periosteum and the dura mater. These sinuses drain into the IJV, which exits via the jugular foramen of the skull
What veins drain into the cavernous sinus?
Ophthalmic veins Superficial cerebral veins Middle cerebral veins Inferior cerebral veins Sphenoparietal veins
How can an infection causing cavernous sinus thrombosis lead to bulging eyes?
Infections can spread intracranially through valveless veins via the connection go the facial vein to the superior ophthalmic vein. The cavernous sinus is found just behind the eye and therefore when inflammed can push the eyes outwards and cause paralysis to the nerves supplying them
Describe the blood supply to the spinal cord
Three longitudinal spinal arteries (1 anterior and 2 posterior) as well as multiple segmental spinal arteries supply the spinal cord