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Protein 14-3-3

CSF protein helpful in diagnosing Cretuzfeldt-Jakob


Narcolepsy CSF findings?

Decreased hypocretin-1 (orexin-A) and hypocretin-2 (orexin-B)


Arachnoid granulations vs. choroid plexus?

Choroid plexi MAKE CSF. Arachnoid granulations ABSORB CSF. Communicating hydrocephalus 2/2 dysfunction of subarachnoid villi (e.g. meningeal infection or SAH)


Length constant vs. time constant?

Length constant = how far down an axon an AP can go. Time constant = how quickly it takes for a membrane to reset. Myelination increases length constant and decreases time constant.