neuro Flashcards
(40 cards)
cold calorics
intact- eyes deviate with cold toward the water, then nystagmus away back to middle - if brainstem is hurt then it wont deviate to the side at all, if cortex hurt it will deviate and wont come back
bilateral intranuclear opthalmoplegia (cant look at nose )
MS - lesion in MLF
when does CT scan sens dec in SAH
after 12 hours
steroids in meningitis?
steroids first then abx in seriously ill with WBC >1000 did better
when to CT before LP
age 60, HIV, CNS dz, sz, abnormal neuro
0-1 month meninigitis abx and bugs
listeria, e coli, gbs - ampt and gent (or 3rd gen cef but not ceftriaxone bc of jaundice )
meninigits VP shunt
staph epi staph aureus
LP positive for cells but negative gram stain
HSV encephalitis
unilateral vision loss, painful, papilledema, pain with eye movements
optic neuritis- MS - might have bilaterael ION- cant look at nose
LP of MS
ncrease protein, IGG, oligoclonal bnds- lots of protein
rapid progressive extreity weakness, limb paralysis after exercise, Low K
acute periodic paralysis, asian male, K shifted into cells after exercise, assn hypo K ***thyrotoxicosis- AD - avoid high carb diet
muscle weakness, fatiguability with diplopia, ptosis
MG classicaly starts in face, wake up in AM ok, worse during the day, worse during counting
autoab vs ach receptors
MG, assn thyoma
tensilon (edrophonium) test
tensilon test- blocks ACHi- ach sticks around longer , patient gets better - side effect brady/sycope
tx MG
physostigmine/neostigmine
exacerbations of MG causes
either exacerbation- or overtreatment - comes in cholingeric BBBB sludge
hx Ca, decreased DTR, calcium channels- failure to release Ach from terminal presynaptic axons of motor neurons
Lambert EAton- weakness improves with use
tx lambert eaton
remove tumor, plamapheresis
ach release blocked at NMJ
botulism- motor and autonomic fxn
causes of botulism
foodborne, wound, infant
diplopia, dysphagia, ptosis, descneding flaccid paralysis, antiAch sxs- drymouth, dilated pupils, normal sensation
botulism
floppy baby, constipation, feeble cry
botulism
tx botulsims
antitoxin, debride wound, high dose pcn
reversible, rapidly ascending paralysis, no paresthesias
tick paralysis - no paresthesias diff from GBS