Neuro-endocrine Interactions Flashcards Preview

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Flashcards in Neuro-endocrine Interactions Deck (21):
1

What is the pituitary gland

Hypophysis
Small endocrine gland at the base of the brain just below hypothalamus

2

What are the two anatomical distinct lobes of the pituitary

Anterio - consist of glandular tissue - adenohypophysis
Posterior - consist of nervous tissue - neurohypophysis

3

How is the release of hormones from the pituitary controlled directly

Posterior pit connects to the hypothalamus by a neural pathway
Anterior pituitary connects via a sp vascularised link

4

What hormones does the anterior pituitary produce

GH
ACTH
TSH
LH
FSH
Prl

5

What e the functions of the hormones secreted form the anterior pituitary

GH - stimulates growth
ACTH - stimulate sad renal cortex
TSH - stimulates thyroid gland
Prl - stimulates lactation
LH - stimulates gonads
FSH - stimulates gonads

6

What hormones does the posterior pituitary produce and what are their functions

ADH - Promotes water retention
Oxytocin - stimulates milk ejection

7

What are the two cell bodies in the hypothalamus

The supraoptic nuclei
Para ventricular nuclei
Clusters of neurones in hypothalamus produce post pit hormones

8

What is the vascular Link between the hypothalamus and the anterior pituitary

The hypothalamic hypophyseal portal system

9

What are the cell types in the anterior pituitary

Corticotrophs
Somatotrophs
Lactotroohs
Thyrotrophs

10

What do corticotrphs prod

Prod acth stim release of cortisol form adrenal cortex

11

What do thyrotrophs produce

Prod TSH which acts on the thyroid gland as a tropic hormone

12

What do lactotrophs produce

Prolactin

13

What do somatotrophs produce

Produce growth hormone

14

What is GH releasing and inhibiting factor

Rf- ghrh

If - somatostatin

15

What is TSH releasing and inhibiting factor

Rf - trh

16

What is Prl releasing and inhibiting factor

Rf - prf

If - prolactin inhib factor pif - dopamine

17

What is acth releasing hormone

Crh

18

What is the releasing factor for LH and FSH

GnRH

19

What does a hypophysectomy do to the material pituitary

Growth stops as removal of GH
Thyroid hormone deficiency
Adrenal Cortex atrophy
Loss of secondary sexual differentiation
Atrophy of gonads
Increased insulin sec

20

What are th effects of a hypophysectomy of the posterior pituitary

Dehydration by polyuria ( abnormal large vol of urine) despite pronounced polydipsia ( great thirst)
Diabetes insipidus above condition
Deficiency of ADH
Little effect form loss of oxytocin

21

What does this system interact with

The hypothalamus and the pituitary