Neuro/Psych 3 Flashcards Preview

ID/LC Step Review > Neuro/Psych 3 > Flashcards

Flashcards in Neuro/Psych 3 Deck (19):
1

What are the neuro comorbidities associated with Down syndrome?

- Intellectual disability
- Early-onset Azlheimer disease

2

What are the characteristic pathologic changes associated with Alzheimer disease?

- Accumulation of intracellular neurofibrillary tangles and extracellular amyloid-beta plaques
- Arise due to amyloid precursor protein gene

3

Which protein comprises neurofibrillary tangles?

Tau protein

It's hyperphosphorylated in AD

4

How does N. meningitidis get access to the CNS?

- Colonizes nasopharynx
- Invades mucosal epithelium => blood stream
- Spread to choroid plexus => BBB

Pharynx => Blood => Choroid plexus => Meninges

5

Purpose of ornithine

- Transports into mitochondria
- Essential for urea formation
- Combines with carbamoyl phosphate in mitochondria to form citrulline

6

What needs to be restricted in your diet if you cannot transport ornithine into the mitochondria?

PROTEIN

- Otherwise ammonia will accumulate => neurological damage

7

Paralysis of the stapedius nerve presentation

- Hyperacusis
aka sensitive to sound
- Facial nerve (CN VII) origin

8

Where do you do a femoral nerve block?

At the inguinal crease

w/ lidocaine

9

Lesion of glossopharyngeal nerve (CN IX)

- Loss of gag reflex (afferent limb)
- Loss of sensation in upper pharynx, posterior tongue, tonsils, middle ear cavity
- Loss of taste sensation on the posterior third of tongue

10

Biceps and brachioradialis reflexes test which spinal nerve roots?

C5-C6

11

Which tracts send info to the ventral posterior lateral nucleus?

- Spinothalamic
- Dorsal column

12

What input is sent into the ventral posterior medical nucleus?

Trigeminal pathway

13

What are lacunar infarctions?

- Small vessel occlusion in penetrating vessels supplying deep brain structures
- Due to lipohyalinosis and microatheroma formation
- Uncontrolled HTN and DM are major risk factors

14

What is serotonin syndrome?

- Any drugs that increase serotonin levels
- Combo of SSRIs and MAOIs
- High dose SSRIs

15

What AA is the precursor for serotonin?

Tryptophan

16

What AA is the precursor for dopamine, epi, norepi and melanin?

Tyrosine

17

Tx for serotonin syndrome

Cyproheptadine

- An antihistamine w/ anti-5-HT1 and 2 receptors

18

What is used for benzo overdose?

Flumazenil

19

Characteristics of zolpidem

- Less potential for tolerance/addition
- Fewer withdrawel sx than benzos
- No anticonvulsant properties
- No muscle relaxing effects
- Rapid onset
- Used for short-term tx of insomnia

Chemically unrelated to benzos