Neurochemistry of Memory Flashcards Preview

Psychiatry > Neurochemistry of Memory > Flashcards

Flashcards in Neurochemistry of Memory Deck (28):
1

This part of the brain is responsible for emotional responses

Amygdala

2

Part of the brain involved in declarartive (explicit) memory

Hippocampus
Medial temporal lobe
Diencephalon

3

Affects mood, hunger, sleep and arousal

Serotonin

4

Influences movement, learning, attention and emotional

Dopamine

5

Undersupply linked to depression

Serotonin
Noradrenaline

6

Oversupply linked to schizophrenia

Dopamine

7

Undersupply linked to tremors and decreased mobility in Parkinsons

Dopamine

8

Undersupply linked to ADHD

Dopamine
Noradrenaline

9

Neurotransmitter that enables muscle action, learning and memory

Acetylcholine

10

Which neurones deteriorate as Alzheimer's disease progresses?

ACh-producing neurones

11

Helps control alertness and arousal

NA

12

Undersupply can depress mood and cause ADHD-like problems

NA

13

Undersupply linked to seizures, tremors and insomnia

GABA (bc its inhibitory so not enough = your body is super excited)

14

Oversupply can stimulate the brain producing migraines or seizures

Glutamate (why some people avoid MSG foods haha)

15

Most frequent neurotransmitter in the CNS

Glutamate

16

Which channels does ACh work on and how?

Inhibits nicotinic ion channels by depolarisation

17

Key role in memory, attention and arousal

ACh

18

Which receptors does glutamate work on?

AMPA
Metabotropic
NMDA

19

This is involved in post-synaptic long term potentiation

Glutamate

20

These receptors produce rapid responses to glutamate

AMPA

21

These receptors are responsible for synaptic plasticity and are key in long term potentiation
-how do they work?

NMDA
-allow Calcium influx

(glutamate responsible for this)
(AMPA also play a role)

22

Agonists reduce or prevent neuro inflammation and modualte mitochondrial function

PPARy

23

Role of ApoE

Cholesterol metabolism
Membrane stability and repair

-problems with this gene in alzheimers

24

Role of tau protein

Stabilises microtubules

25

Purpose of striatal interneurones

Motor control

26

Purpose of the nucelus basalis of Meynert?

Attention/arousal

27

Purpose of medial septal nucleus?

Learning and memory

28

Alzheimers meds/ drugs which prevent ACh breakdown?

Galantamine
Rivestigmine
Donepezil