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Flashcards in neurocog disorders Deck (35)
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1

major NCD have ____decline, mild NCD have____decline

significant; modest

2

domains evaluated for NCD (6)

1. complex attn
2. executive fxn
3. learning/memory
4. language
5. perceptual motor
6. social cognition

3

risk factors for AD (4)

1. advanced age
2. famhx
3. down's syndrome
4. apolipoprotein E4

4

neurofibrillay tangles, neuritic plaques, excess amyloid

only things that can definitively dx AD

5

binswanger's disease

vascular disease/multi-infarct dementia

6

2nd most common type of dementia

multi-infarct dementia

7

subclinical parkinsonism, psychosis, autonomic dysfxn, gradual progressive cognitive impairment

lewy body disease

8

tx of lewy body disease

cholinesterase inhibs

9

what must be avoided in tx of lewy body disease

antipsychotics

10

impairment of the temporal and frontal lobes; occurs in 50's, disinhibition/apathy, language problems, steadily progressive

pick's disease (frontotemporal disease)

11

mild repetitive concussions, followed 8-10 yrs later by neuropsych sx

chronic traumatic encephalopathy

12

types of subcortical disease (4)

1. PD
2. MS
3. HD
4. vascular disease

13

huntington's is what mode of inheritance

autosomal dominant

14

choreoathtoid movements, changes in mood/personality, flat affect, rapid & soft speech

HD

15

triad of normal pressure hydrocephalus

1. confusion
2. ataxic gait
3. urinary incontinence

16

how to determine if ventriculo-peritoneal shunt is beneficial for tx of normal pressure hydrocephalus

LP

17

once traumatic brain injury is stabilized and it doesn't improve

static encephalopathy

18

tx of wernicke's encephalopathy

thiamine

19

delirium, ocular changes, gait disturbance in alcoholics

wernicke's encephalopathy

20

what is mahor/mild neurocognitive disorder, amnestic-confabulatory type

korsakoff's syndrome

21

rash, fatigue, HA, focal neuro signs, encephalitis, cognitive sx

lyme disease

22

tx of lyme disease

Abx

23

onset middle-old age, psych disturbances, tremor

cruetzfeldt-jakob

24

develops over a short period and fluctuates

delirium

25

____% hospitalized patients are affected by delirium

30%

26

risk factors for delirium (4)

1. age
2. nursing home
3. pre-existing brain damage
4. male

27

tx of MCI

encourage catastrophization

28

initial labs for NCD

1. CBC
2. CMP
3. Vit B12
4. thyroid studies

29

what genes can be assessed for early onset AD

Prensilin 1/2, APP

30

who determines decision making capacity

attending physician