Flashcards in neurocog disorders Deck (35)
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1
major NCD have ____decline, mild NCD have____decline
significant; modest
2
domains evaluated for NCD (6)
1. complex attn
2. executive fxn
3. learning/memory
4. language
5. perceptual motor
6. social cognition
3
risk factors for AD (4)
1. advanced age
2. famhx
3. down's syndrome
4. apolipoprotein E4
4
neurofibrillay tangles, neuritic plaques, excess amyloid
only things that can definitively dx AD
5
binswanger's disease
vascular disease/multi-infarct dementia
6
2nd most common type of dementia
multi-infarct dementia
7
subclinical parkinsonism, psychosis, autonomic dysfxn, gradual progressive cognitive impairment
lewy body disease
8
tx of lewy body disease
cholinesterase inhibs
9
what must be avoided in tx of lewy body disease
antipsychotics
10
impairment of the temporal and frontal lobes; occurs in 50's, disinhibition/apathy, language problems, steadily progressive
pick's disease (frontotemporal disease)
11
mild repetitive concussions, followed 8-10 yrs later by neuropsych sx
chronic traumatic encephalopathy
12
types of subcortical disease (4)
1. PD
2. MS
3. HD
4. vascular disease
13
huntington's is what mode of inheritance
autosomal dominant
14
choreoathtoid movements, changes in mood/personality, flat affect, rapid & soft speech
HD
15
triad of normal pressure hydrocephalus
1. confusion
2. ataxic gait
3. urinary incontinence
16
how to determine if ventriculo-peritoneal shunt is beneficial for tx of normal pressure hydrocephalus
LP
17
once traumatic brain injury is stabilized and it doesn't improve
static encephalopathy
18
tx of wernicke's encephalopathy
thiamine
19
delirium, ocular changes, gait disturbance in alcoholics
wernicke's encephalopathy
20
what is mahor/mild neurocognitive disorder, amnestic-confabulatory type
korsakoff's syndrome
21
rash, fatigue, HA, focal neuro signs, encephalitis, cognitive sx
lyme disease
22
tx of lyme disease
Abx
23
onset middle-old age, psych disturbances, tremor
cruetzfeldt-jakob
24
develops over a short period and fluctuates
delirium
25
____% hospitalized patients are affected by delirium
30%
26
risk factors for delirium (4)
1. age
2. nursing home
3. pre-existing brain damage
4. male
27
tx of MCI
encourage catastrophization
28
initial labs for NCD
1. CBC
2. CMP
3. Vit B12
4. thyroid studies
29
what genes can be assessed for early onset AD
Prensilin 1/2, APP
30
