substance use

Question 1

consumption amounts that increase the likelihood of health consequences

Answer 1

risky use

Question 2

A state of adaptation that is manifested by a withdrawal syndrome that can be produced by abrupt cessation of a substance or by tolerance to the substance

Answer 2

physical dependence

Question 3

A primary, chronic, neurobiologic disease, with genetic, psychosocial, and environmental factors influencing its development and manifestations.

Answer 3

addiction

Question 4

use of any drug that deviates from approved social or medical patterns

Answer 4

abuse

Question 5

applies to drugs that are prescribed by physicians and not used properly

Answer 5

misuse

Question 6

Ability of one drug to be substituted for another producing the same effects physiologically and psychologically

Answer 6

cross tolerance

Question 7

what is crucial to memory formation and gives motivation to repeat pleasurable experiences?

Answer 7

dopamine

Question 8

dx for substance us include____for >____

Answer 8

clinical distress/impairment for >12 mon

Question 9

4 categories defining substance use

Answer 9

1. impaired control
2. social impairment
3. risky use
4. pharmacological criteria

Question 10

craving indicates____

Answer 10

impaired control

Question 11

phamacoloical criteria include____ and ____

Answer 11

tolerance and withdrawal

Question 12

which theory of alcohol use pathogenesis: direct activation of the reward centers

Answer 12

positive-affect regulation

Question 13

which theory of alcohol use pathogenesis: self-medication

Answer 13

negative affect regulation

Question 14

which theory of alcohol use pathogenesis: some people are just more prone to develop a use disorder

Answer 14

pharmacological vulnerability

Question 15

which theory of alcohol use pathogenesis: alcohol consumption is part of an overall picture of social deviance arising in childhood and resulting from deficient socialization

Answer 15

deviance proneness

Question 16

confusion + ataxia + ocular abnormalities

Answer 16

wernickes

Question 17

alcohol is associated with what eye movement

Answer 17

nystagmus

Question 18

peak alcohol withdrawal occurs when?

Answer 18

48 hrs, can last 5 days

Question 19

clouding of sensorium, hallucinations, tachycardia, HTN , hyperthermia, diaphresis, asscd with alcohol

Answer 19

delirium tremens

Question 20

risk factors for delirium tremors (6)

Answer 20

1. h/o sustained drinking
2. h/x previous DT
3. age >30
4. concurrent illness
5. significant alcohol withdrawl
6. longer period since last drink

Question 21

what is CIWA

Answer 21

clinical institute withdrawal assessment – alcohol

Question 22

opioid antag used as maintenance tx for alcohol use disorder

Answer 22

naltrexone

Question 23

which drug used in alcohol use disorder works on GABA and glutamate?

Answer 23

acamprosate

Question 24

caffeine intoxication occurs at what level

Answer 24

> 250 mg

Question 25

caffeine withdrawal defined as ___sx within ___hours

Answer 25

3 sx within 24 hrs

Question 26

HA, fatigue, dysphoric, flue-like sx, difficulty concentating

Answer 26

caffeine withdrawl

Question 27

chronic weed use can lead to

Answer 27

amotivational syndrome

Question 28

K2 synthestic cannabinoid can induce____

Answer 28

psychosis

Question 29

which drug is NOT associated with withdrawal?

Answer 29

hallucinogens, inhalants

Question 30

nystagmus, dilated pupils, violent behavior, dissociative sx, HTN

Answer 30

phencyclidine

Question 31

what drugs are in the other hallucinogen use group

Answer 31

MDMA, mescaline, psilocybin, LSD

Question 32

COWS utilization

Answer 32

opioid withdrawal scale

Question 33

long-acting synthetic opioid agonist, Prevent withdrawal, Reduce cravings

Answer 33

methadone

Question 34

reduce or eliminate withdrawal symptoms associated with opioid dependence and carries a low risk of overdose.

Answer 34

buprenorphine

Question 35

opioid antag that prevents euphoric effects without any potential for abuse

Answer 35

naltrexone

Question 36

autonomic hyperactivity, hand tremor, hallucinations with reality intact

Answer 36

sedative/hyponotic/anxiolytic withdrawal

Question 37

what is a necessary criteria for definition of stimulant withdrawal?

Answer 37

dysphoric mood

Question 38

which substance is not related with intoxication?

Answer 38

tobacco

Question 39

short term residential tx typically lasts how long

Answer 39

3-6 week inpatient with extended outpatient tx

Question 40

long term residential care tx lasts how long

Answer 40

6-12 mon

Question 41

what test is used for confirmatory testing?

Answer 41

gas chromatography mass spec

Question 42

______are qualitative and gas chromatography is _____

Answer 42

qualitative; quantitative