Flashcards in substance use Deck (42)
Loading flashcards...
1
consumption amounts that increase the likelihood of health consequences
risky use
2
A state of adaptation that is manifested by a withdrawal syndrome that can be produced by abrupt cessation of a substance or by tolerance to the substance
physical dependence
3
A primary, chronic, neurobiologic disease, with genetic, psychosocial, and environmental factors influencing its development and manifestations.
addiction
4
use of any drug that deviates from approved social or medical patterns
abuse
5
applies to drugs that are prescribed by physicians and not used properly
misuse
6
Ability of one drug to be substituted for another producing the same effects physiologically and psychologically
cross tolerance
7
what is crucial to memory formation and gives motivation to repeat pleasurable experiences?
dopamine
8
dx for substance us include____for >____
clinical distress/impairment for >12 mon
9
4 categories defining substance use
1. impaired control
2. social impairment
3. risky use
4. pharmacological criteria
10
craving indicates____
impaired control
11
phamacoloical criteria include____ and ____
tolerance and withdrawal
12
which theory of alcohol use pathogenesis: direct activation of the reward centers
positive-affect regulation
13
which theory of alcohol use pathogenesis: self-medication
negative affect regulation
14
which theory of alcohol use pathogenesis: some people are just more prone to develop a use disorder
pharmacological vulnerability
15
which theory of alcohol use pathogenesis: alcohol consumption is part of an overall picture of social deviance arising in childhood and resulting from deficient socialization
deviance proneness
16
confusion + ataxia + ocular abnormalities
wernickes
17
alcohol is associated with what eye movement
nystagmus
18
peak alcohol withdrawal occurs when?
48 hrs, can last 5 days
19
clouding of sensorium, hallucinations, tachycardia, HTN , hyperthermia, diaphresis, asscd with alcohol
delirium tremens
20
risk factors for delirium tremors (6)
1. h/o sustained drinking
2. h/x previous DT
3. age >30
4. concurrent illness
5. significant alcohol withdrawl
6. longer period since last drink
21
what is CIWA
clinical institute withdrawal assessment – alcohol
22
opioid antag used as maintenance tx for alcohol use disorder
naltrexone
23
which drug used in alcohol use disorder works on GABA and glutamate?
acamprosate
24
caffeine intoxication occurs at what level
>250 mg
25
caffeine withdrawal defined as ___sx within ___hours
3 sx within 24 hrs
26
HA, fatigue, dysphoric, flue-like sx, difficulty concentating
caffeine withdrawl
27
chronic weed use can lead to
amotivational syndrome
28
K2 synthestic cannabinoid can induce____
psychosis
29
which drug is NOT associated with withdrawal?
hallucinogens, inhalants
30
