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Flashcards in substance use Deck (42)
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1

consumption amounts that increase the likelihood of health consequences

risky use

2

A state of adaptation that is manifested by a withdrawal syndrome that can be produced by abrupt cessation of a substance or by tolerance to the substance

physical dependence

3

A primary, chronic, neurobiologic disease, with genetic, psychosocial, and environmental factors influencing its development and manifestations.

addiction

4

use of any drug that deviates from approved social or medical patterns

abuse

5

applies to drugs that are prescribed by physicians and not used properly

misuse

6

Ability of one drug to be substituted for another producing the same effects physiologically and psychologically

cross tolerance

7

what is crucial to memory formation and gives motivation to repeat pleasurable experiences?

dopamine

8

dx for substance us include____for >____

clinical distress/impairment for >12 mon

9

4 categories defining substance use

1. impaired control
2. social impairment
3. risky use
4. pharmacological criteria

10

craving indicates____

impaired control

11

phamacoloical criteria include____ and ____

tolerance and withdrawal

12

which theory of alcohol use pathogenesis: direct activation of the reward centers

positive-affect regulation

13

which theory of alcohol use pathogenesis: self-medication

negative affect regulation

14

which theory of alcohol use pathogenesis: some people are just more prone to develop a use disorder

pharmacological vulnerability

15

which theory of alcohol use pathogenesis: alcohol consumption is part of an overall picture of social deviance arising in childhood and resulting from deficient socialization

deviance proneness

16

confusion + ataxia + ocular abnormalities

wernickes

17

alcohol is associated with what eye movement

nystagmus

18

peak alcohol withdrawal occurs when?

48 hrs, can last 5 days

19

clouding of sensorium, hallucinations, tachycardia, HTN , hyperthermia, diaphresis, asscd with alcohol

delirium tremens

20

risk factors for delirium tremors (6)

1. h/o sustained drinking
2. h/x previous DT
3. age >30
4. concurrent illness
5. significant alcohol withdrawl
6. longer period since last drink

21

what is CIWA

clinical institute withdrawal assessment – alcohol

22

opioid antag used as maintenance tx for alcohol use disorder

naltrexone

23

which drug used in alcohol use disorder works on GABA and glutamate?

acamprosate

24

caffeine intoxication occurs at what level

>250 mg

25

caffeine withdrawal defined as ___sx within ___hours

3 sx within 24 hrs

26

HA, fatigue, dysphoric, flue-like sx, difficulty concentating

caffeine withdrawl

27

chronic weed use can lead to

amotivational syndrome

28

K2 synthestic cannabinoid can induce____

psychosis

29

which drug is NOT associated with withdrawal?

hallucinogens, inhalants

30

nystagmus, dilated pupils, violent behavior, dissociative sx, HTN

phencyclidine