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Flashcards in somatic therapies Deck (40)
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1

metabolism of SSRI

hepatic

2

lethargy, restlessness, mental confusion, flushing, diaphoresis, termor

serotonin syndrome

3

serotonin occurs when what are combined

>1 SSRI, or MAOi

4

subclinical serotonin syndrome

mild cognitive complaints, mild tremor, diaphoresis

5

at lower doses, venlafaxine acts on_____, at higher doses it acts on_____

inhibits serotonin reuptake; inhibits NE and DA reuptake

6

high doses of venlafaxine assc'd with what SE?

sedation

7

which med is very sensitive to discontinuation syndrome

venlafaxine

8

buproprion MOA

weak reuptake inhib of DA and NE

9

at doses >450 of wellbutrin, what SE may occur?

seizure

10

MOA of vilazodone

SSRI and 5HT receptor partial agonist

11

MOA of trazadone

weak inhibitor of serotonin + blocks 5HT2 receptors

12

utilization of trazadone

sleep agent

13

MOA of mirtazapine

antag at postsynaptic 5HT2, 5HT3, central alpha1

14

uses of mirtazapine

MDD, sleep aid

15

what class is chlomipramine

TCA

16

what makes chlomipramine stand out from other TCA

relatively selective serotonin reuptake inhib

17

anxiety, irritability, insomnia, HA, nausea, malaise, motor disturbance

discontinuation syndrome

18

does melancholic depression or bipolar depression respond better to meds

melancholic depression

19

choice med for tx of MDD during pregnancy

sertraline

20

the most widely prescribed class of psychotropic drugs

benzos

21

tx of OCD

1. higher doses SSRI
2. clomipramine

22

MOA of benzos

GABA agonist

23

buspirone is effective in treating what type of anxiety

GAD

24

MOA of buspirone

dendritic 5HT agonist

25

1st line fro acute psychosis

high potency SGA or haloperidol

26

muscle rigidity, high fever, delirium, autonomic instability, elevated serum CPK and LFT

neuroleptic malignant syndrome

27

tx of neuroleptic malignant syndrome

1.stop med
2. bromocriptine

28

occurs within 1st 4 days of antipsychotic administration, sustained contraction of neck muscles

acute dystonic rxn

29

tx of acute dystonia

benztropine or diphenhydramine

30

can occur within 1st few weeks of antipsychotic initiation, anxiety, tension, restlessness, agiatation

akathesia