neurological injuries/illnesses Flashcards

1
Q

brain death

A

no motor response, no brainstem reflexes
- negative dolls eye reflex

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2
Q

vegetative state

A

brainstem maintenance, hypothalamic function, no awareness of self or surroundings

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3
Q

2 outcomes of global ischemia

A

watershed infarcts and reperfusion injuries

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4
Q

monroe-kellie hypothesis

A

displacement of fluid contents being a reduction in venous blood flow and CSF content

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5
Q

cushing’s triad

A

a sign of high ICP
- hypertension
- bradycardia
- irregular respirations

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6
Q

vasogenic cerebral edema

A

BBB compromised which causes inflammation leading to high ICP

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7
Q

cytotoxic cerebral edema

A

increase intracellular fluid shift which causes ischemia leading to a high ICP

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8
Q

ischemic CVA

A

caused by a thrombus/embolus and cause 80% of all strokes

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9
Q

TIA

A

a warning of a CVA and only present with ischemia

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10
Q

thrombectomy

A

treatment of ischemic CVA
- blood clot removed via suction through catheter insertion

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11
Q

angioplasty

A

treatment of ischemic stroke
- stent inserted and balloon blown up to widen vessel

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12
Q

hemorrhagic stroke

A

1st s&s will be headache, vomiting high BP with sudden onset

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13
Q

hemorrhagic stroke treatment

A

hypertonic NS (3%NaCl) , mannitol (osmotic diuretic)

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14
Q

AVM

A

characteristic of slow onset of neuro deficits
- steals blood flow from surrounding area d/t no capillary network

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15
Q

sign of aortic aneurysm

A

bruits

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16
Q

epidural hematoma

A

between dura (protective brain layer) and skull

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17
Q

common cause of epidural hematoma

A

skull fracture

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18
Q

subdural hematoma

A

between dura (protective brain layer) and subdural space (just below protective layer near brain)

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19
Q

common cause of subdural hematoma

A

accel/decel injuries

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20
Q

characteristic of acute hematoma

A

high morbidity and mortality

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21
Q

characteristic of chronic hematoma

A

very slow onset and due to brain atrophy

22
Q

main focus when treating hematoma

A

decrease ICP
- do this through osmotic diuretic and antihypertensives

23
Q

brain parenchyma infection

A

encephalitis

24
Q

spinal cord infection

25
most common cause of infection
bacteria
26
type of infection that is less fatal
viral/viruses
27
purulent meningitis
bacterial
28
lymphocytic meningitis
viral
29
highest mortality meningitis bacteria
strep.pneumoniae - 34%
30
meningitis antibiotics
amoxicillin, vancomycin, 3rd gen cephalosporins - add in dexamethasone as treatment
31
metastatic cancer/tumors
tumor starts in one tissue but spreads to others
32
alkylating agents (DNA damage)
chemotherapy used for tumors/cancer - temozolomide
33
temozolomide
type of chemotherapy
34
idiopathic seizure
genetic origin with no known cause
35
symptomatic seizure
caused by a brain injury
36
focal seizures
affect group of neurons in one hemisphere
37
generalized seizures
both hemispheres involved
38
status epilepticus
can be any seizure type that progresses to unstoppable state which is life threatening
39
alzheimers
caused decreased Ach synthesis - behavioural changes
40
management of alzheimer's
increase Ach through cholinesterase inhibitors
41
parkinsons
caused by lack of dopamine; inability to filter out extra movements - 2nd most common form of dementia
42
management of parkinson's
increase dopamine through dopamine agonists
43
brainstem
pons, medulla, midbrain
44
occurence of dreams and nightmares sleep stage
REM
45
these are all signs of what stage of sleep: fast HR, high BP, fast RR, temp fluctuation, brain resembles wakeful state
REM
46
insomnia
related to cortisol and have difficulties with initiation and duration of sleep
47
obstructive sleep apnea
due to collapse of upper airway - prominent in REM d/t muscle relaxation
48
central apnea
deficit in brain stem and resp centers where signals aren't sent - commonly seen in brain injuries and cerebral edema
49
schizophrenia positive symptoms
hallucinations, delusions
50
schizophrenia negative symptoms
withdrawn, apathetic, lack of motivation
51
neuroleptic malignant syndrome
VS crisis - hyperthermia, diaphoresis, unstable BP
52
addiction
forms from ventromedial prefrontal cortex which deals with impulse control