Neurotransmission Flashcards
Biological Approach 1.4 (17 cards)
Structure of a neuron
Action potential
The electrical impulse that travels along the body of the neuron
Process of neurotransmission (6)
- Electrical impulses travel along body of neuron
- Travel down axon of neuron
- Releases neurotransmitters that are stored in the neuron’s terminal buttons
- Neurotransmitters released into the gap between neurons - synapses
- Neurotransmitters fit into receptor sites on pstsynaptic membrane (like lock and key)
- Broken down by an enzyme or reabsorbed by the terminal buttons (reuptake)
Neurotransmitters
Natural chemical messengers that transmit information from one neuron to another
Excitatory neurotransmitters
Increase the likelihood of a neuron firing by depolarising the neuron (like acetylcholine)
Inhibitory neurotransmitters
Decrease likelihood of a neuron firing by hyperpolarising the neuron (like GABA)
Metabotropic neurotransmitters
Only indirectly affect neuron and are considered neither excitatory nor inhibitory (serotonin, dopamine, norepinephrine)
Acetylcholine
Plays a role in the consolidation of memory in the hippocampus
Dopamine
Controls brain’s reward and pleasure centers - key role in motivation
* low levels are linked to addictive behaviour
Norepinephrine
Arousal and alertness
Serotonin
Sleep, arousal levels and emotion
Limitations of neurotransmission (4)
- research can only be done indirectly
- over-reliance on fMRI technology means limitations of technique apply here
- many studies are on animals - lack of reliability and generalisability
- research on humans is correlational in nature - can’t establish cause and effect (bidirectional ambiguity)
- argument that neurotransmitters are the cause of behaviour is reductionist - oversimplification of human behaviour
Strengths of neurotransmitters (3)
- they have led to successful treatments for certain behaviours (drugs developed for psychological disorders)
- experimental research that supports the role of them in behaviour
- can be replicated to establish reliability
Agonist
Chemicals that mimic a neurotransmitter at the receptor site and, thus, strengthen its effects
Antagonist
Drugs that block the receptor site and do not allow the neurotransmitter to do its job, so no action potential is sent down the neuron
Endogenous agonist
Biological chemical that binds to a receptor site (already part of our nervous system)
* all neurotransmitters are agonists for receptor sites (acetylcholine is an antagonist for ACh receptor sites)
Exogenous agonists
External drugs that attach to a receptor site for a neurotransmitter and excite the neuron
* nicotine for ACh