Non- Hodgkins lymphoma Flashcards

1
Q

_____ lymphoma Occurs anywhere in the body that lymph can travel

A

Non- Hodgkin’s

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2
Q

Non- Hodgkin’s spreads

A

randomly and in no order

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3
Q

For Non- Hodgkin’s ionizing radiation can

A

cause it

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4
Q

For Non- Hodgkin’s it is More common in older people, with ___ being the median age

A

67

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5
Q

Non-Hodgkin’s Lymphoma Common clinical presentations are

A

swollen lymph nodes, night sweats, fatigue, itching, and weight loss (B symptoms)

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6
Q

Non- Hodgkin’s common locations include

A

lymph nodes, Gl tract (Peyer’s patches), and Waldeyer’s ring

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7
Q

For Non-Hodgkin’s Lymphoma the chemotherapy used is

A

CHOP (cyclophosphamide, vincristine, doxorubicin, and prednisone)

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8
Q

Non-Hodgkin’s Lymphoma pathology includes

A

B-cell and T-cell neoplasms with 31 subtypes

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9
Q

Non-Hodgkin’s Lymphomas are classified as

A

follicular/nodular or diffuse(#1)

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10
Q

Non-Hodgkin’s Lymphoma uses what staging system

A

ANN arbor

  • lugano classification type of ANN arbor staging
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11
Q

when it comes to lymph spread unlike HL NHL spreads _______

A

randomly

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12
Q

non Hodgkins lymphoma

A
  • spreads radomoly
  • lymphoid tissue : primary and peripheral contain B and T precursor cells
  • classified as follicular or diffuse
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13
Q

Non - Hodgkins etiology

A
  • unknown (genetic alterations of the B or T lymphocytes)

identified risk factors

-ionizing radiation
- Ankylosing spondylitis

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14
Q

clinical presentation forNHL

A
  • similar to HD
  • Unlike HD, NHL can arise in lymph nodes , GI tract, waldezyers ring , CNS (AIDS)
  • similar to Hodgkin
  • shortness of breath - lung involvement
  • abdominal pain or change of bowel habits may indicate pelvic disease
  • GI, CNS, Waldeyer ring
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15
Q

pathology for NHL includes

A

two types

  • primary (central lymph tissue)
  • precursor cells both B and T cells
  • occurs in bone marrow and thymus
  • Periphery (secondary lymph tissues)
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16
Q

NHL histologic classification includes:

A

Follicular (nodular) - 40%

< B- cell origin

<not found in children

diffuse- 60%

  • B or T cell origin
  • it runs a more aggressive course spreading quickly to other nodes and extra nodal nodes