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Flashcards in Normocytic Anemia Deck (10):
1

2 types of hemolytic anemia

Intrinsic and extrinsic

2

Inherited disorders characterized by either defects in the RBC's plasma membrane, defects in certain intracellular enzymes, or abnormal hemoglobin

Intrinsic hemolytic anemia

3

Hemolytic anemia affects RBC in what way

Their elasticity or ability to protect itself from mechanical and chemical stresses as it circulates through the spleen and transverses narrow tissue capillaries

4

Acquired disorders associated with some external injury to otherwise normal RBC.

Extrinsic hemolytic anemias

5

Clinical clues that suggest hemolysis

1) Sudden or rapid onset of anemia (fall in hemoglobin more than 1 g/dl/day) in a patient with no evidence of bleeding
2) Jaundice
3) splengomegaly 4) hx of anemia since childhood
5) family hx 6) autoimmune disease, leukemia, lymphoma 7) use of drugs associated w/ hemoysis

6

When spleen removes old RBC from circulation, heme portion is broken down into

Iron and bilirubin

7

Bone marrow failure is AKA

Aplastic Anemia

8

A reduction of RBC, WBC, and platelets in the bood

pancytopenia

9

Dignosis of aplastic anemia is confirmed with

Bone marrow biopsy demonstrating reduced numbers of RBC, WBC, and megakaryocytes on bone marrow biopsy

10

Cause of death in people with aplastic anemia

Infection or bleeding