Nucleic Acids Flashcards Preview

Biology > Nucleic Acids > Flashcards

Flashcards in Nucleic Acids Deck (38):
1

monomers of nucleic acids

nucleotide

2

nucleotides made up of

phosphate group,
sugar,
nitrogenous base

3

charge of phosphate group in nucleotides

negative

4

sugar in nucleotides

5 carbons, deoxyribose and ribose (dna and rna)

5

nitrogenous bases (2)

pyramidines or purines

6

purine

larger, A & G

7

pyramidine

smaller, C, U, T

8

dna bases

ACGT

9

Rna bases

ACGU

10

what is the base connected to; bond name

1st carbon; n glycosidic bond

11

base + sugar

nucleoside

12

3 non-genetic functions of nucleotides

carry energy, coenzymes, signaling

13

chemical energy nucleotides carry

ATP

14

H used to think what held genetic info and why

protein (20 amino acids vs dna 4 nucleotides

15

H who used mice and bacteria, what kind

griffith; pneumonia

16

H griffith used which strain on the first mouse, outcome

S STRAIN of S pneumoniae, dies

17

H, griffith, which strain has a sugar capsule and is it deadly

S strain & is deadly

18

H griffith used this strain on 2nd mouse and outcome

R strain, lived

19

H, griffith, third mouse

s strain heated, mouse lived

20

H, griffith last mice

injected r and heated s strains and mouse died, extracted s from dead mouse and injected into new one & mouse died

21

H, Griffith importance of study

realized something (genetic information) was being passed from cell to cell

22

H 2nd group of people

avery and mcleod

23

H what did avery and mcleod do

broke open capsules and separated biological parts

24

H what did avery and mcleod use (tool) to separate

column

25

H what did avery and mcleod do to see results

added the parts to r-strain cells

26

H avery and mcleod conclusion and results of the last part of expiriment

DNA only changed the strain; conclusion: dna holds genetic info

27

H third people, used bacteriophage

*hershey* and chase

28

H bacteriophage

viruses attacking bacteria cell; most abundant biological entity

29

H what did hershey use to determine and mark to see which part infects

bacteriophage, radioactive isotopes- labeled cells

30

H, hershey, which parts labeled with what

Dna- 32P (has a phosphate group)
Protein- 35S (sulfur)

31

H, outcome of hersheys expiriment

only p (dna) was in cell, not s (protein)

32

H what three were involved in structure (picture)

franklin-took picture
crick and watson- used picture

33

H what did crick and watson do

realized the shape was a helix, then double helix

34

H chargaff

worked with the bases, recorded the percent of each in various species

35

on what basis does agarose gel electrophoresis separate molecules

size, shape, charge

36

explain migration according to charge

the pos/neg charge makes it move either way

37

why is glycerol added to the solutions before they are loaded into the wells

to weigh them down

38

2 nucleic acids

dna and rna