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Flashcards in Numbers Deck (45)
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1
Q

what is the onset of midadolam?

A

30-60 seconds

2
Q

what is the duration of midazolam?

A

15-80 minutes

3
Q

What is the onset of lorazepam?

A

1-2 minutes

4
Q

What is the duration of lorazepam?

A

6-10 hours

5
Q

What percent of receptors bound by midazolam gives anxiolysis?

A

20-30%

6
Q

What percent of receptors bound by midazolam causes sedation?

A

30-50%

7
Q

What percent of receptors bound by midazolam causes unconsciousness?

A

60%

8
Q

What is the PO dose of midazolam for kids?

A

0.5mg/kg up to 15mg

9
Q

What dose of Midazolam is used for IV sedation?

A

0.5-4mg initial dose then 1-7mg/hour

10
Q

What dose of midazolam is used for IV induction?

A

0.1-0.2mg/kg

11
Q

What dose of Diazepam is used for suppression of siezure activity?

A

0.1mg/kg

12
Q

What % of oral Midaz makes it past 1st pass?

A

50%

13
Q

how much of midaz is bound to protein?

A

90-98%

14
Q

what is the pK of midaz?

A

6.15

15
Q

What is the dose of flumazenil?

A

0.1-0.2 mg repeated up to 3 mg

16
Q

what is the pH of thiopental?

A

10.5

17
Q

What is the onset of thiopental?

A

30-40 seconds

18
Q

what is the duration of thiopental?

A

5-8 minutes

19
Q

What % of thiopental is bound to protein?

A

80%

20
Q

what is the IV induction dose of methohexital?

A

1-1.5mg/kg

21
Q

What is a rectal dose of methohexital?

A

20-30mg/kg

22
Q

What are the components of Proopofol?

A
1% propofol
10% soybean oil
2.25% glycerol
1.2% egg lecithin
0.005% disodium edetate
23
Q

What is the induction dose of propofol?

A

1-2.5mg/kg

24
Q

What is the onset of propofol?

A

30 seconds

25
Q

Waht is the duration of propofol?

A

4-8 minutes

26
Q

What is the distribution half life of propofol?

A

2-8 minutes

27
Q

What % of propofol is metabolized by the liver?

A

70%

28
Q

What % of propofol is metabolized in the lungs?

A

30%

29
Q

What % of propofol is protein bound?

A

98%

30
Q

What is an IV sedation dose of propofol?

A

25-100mcg/kg/min

31
Q

What is a TIVA dose of propofol?

A

100-200mcg/kg/min

32
Q

What % of etomidate is glycerol?

A

35%

33
Q

What is the onset of etomidate?

A

30 seconds

34
Q

What is the duration of etomidate?

A

4-8 minutes

35
Q

What % of etomidate is bound to protein?

A

76%

36
Q

What is the elimination half time of etomidate?

A

2.6 hours

37
Q

What is the IV onset of ketamine?

A

30 seconds

38
Q

What is the IM onset of ketamine?

A

3-4 minutes

39
Q

What is the Duration of ketamine IV?

A

5-10 (or 10-15 depending on the slide)

40
Q

What is the IM duration of ketamine?

A

12-25 min

41
Q

What is the elimination time of ketamine?

A

2.5 hours

42
Q

What % of ketamine is protein bound?

A

27%

43
Q

What is an analgesia subanesthetic dose of ketamine?

A

0.1-0.5 mg/kg/hour

44
Q

What is the IV induction dose of ketamine?

A

1-2mg/kg

45
Q

What is the IM induction dose of ketamine?

A

4-8mg/kg