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Flashcards in Odontogenic tumors Deck (43)
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1

name the cardinal histologic features of odontogenic epithelium (4)

- palisading of the basilar epithelium
- palisading epithelial cells have antibasilar nuclei
- palisading cells have a basilar clear zone within the cytoplasm
- centrally, odontogenic islands are comprised of polygonal cells with long intracellular desmosomal bridges reminiscent of the stellate reticulum

2

which of the 4 cardinal histologic features of odontogenic epithelium is absent in CAA?

stellate reticulum-like cells

3

what are the 4 architecture arrangements of odontogenic epithelium?

- plexiform ribbons
- round follicles
- anastomosing trabeculae
- ink drop structures

4

which architecture arrangement of epithelium is pathognomonic for odontogenic epithelium?

ink drop structures

5

what is required to produce mineralized dental matrix in a tumor?

an odontoblastic component
(because of the process of reciprocal induction, there must be ameloblasts to signal odontoblasts to make dentin which in turn signal ameloblasts to make enamel).

6

what does the term ''odonto'' imply in a tumor name?

the tumor has mineralized dental matrix (thus an odontoblastic component)

7

what does the term ''fibro'' imply in a tumor name?

derived from the dental papilla

8

what is a mixed tumor?

when the neoplastic odontogenic epithelium is capable is capable of inducing the develpoment of dental papilla-like ectomesenchyme

9

how does a pathologist determine what the umor type is?

first by identifying if odontogenic epithelium is present. Then by identifiying if there is a component of either dental papilla derived tissues, mineralized dental matrices or dental follicule derived tissues.

10

what odontogenic tumors present with odontogenic induction?

ameloblastic fibroma
feline inductive odontogenic tumor
ameloblastic fibro-odontoma
odontoameloblastoma
odontoma

11

which odontogenic tumors lack odontogenic induction?

POF
conventional ameloblastoma
CAA
Amyloid producting ameloblastoma
odontogenic myxoma
cementoblastoma
nodular hypercementosis

12

what are the malignant odontogenic tumors?

ameloblastic fibro-odontoma
ameloblastic fibrosarcoma
ameloblastic carcinoma
Odontogenic myxoma
primary intraosseous squamous cell carcinoma (wiggs)

13

What is the other name for amyloid-producing ameloblastoma?

amyloid-producing odontogenic tumor (APOT)

14

what is the most common odontogenic tumor in dogs?

caa

15

what breeds may be overrepresented when it comes to CAA?

golden retrievers
akitas
cocker spaniels
shetland sheepdogs

16

what tissues does the CAA originate from?

rest of serres

17

what are the unique features of CAA on histo?

- does not demontrate stellate reticulum-like features.
- has an internal sheet of interlocking polygonal epithelial cells reminiscent of the epithelial cells of the stratum spinosum of the skin or oral mucosa ( This is what the term ''acanthomatous'' refers to)

18

what type of ameloblastoma commonly features cystic degeneration?

conventional ameloblastoma

19

what differentiates CAA from conventional ameloblastoma

CAA does NOT present with the stellate-reticulum-like cells
other cardinal signs of odontogenic epithelium are present in both

20

what tumor presents in the cat associated with an unerupted maxillary canine?

feline inductive odontogenic tumor

21

what odontogenic tumor appears in young (8-18 months old) cats?

feline inductive odontogenic tumor

22

what odontogenic tumor looks like a honeycomb on x-ray?

odontogenic myxoma

23

what is the only tumor derived form the ectomesenchyme of the dental papilla?

myxomatous tumor of the jaw
(odontogenic myxoma)

24

what are the 3 mixed odontogenic tumors?

odontoameloblastoma
ameloblastic fibro-odontoma
odontoma

25

what would be the difference between odontomas and odontogenic dysplasia?

odontoma: neoplastic or hamartomatous lesion
Odontogenic dysplasia: (elodontoma) caused by inflammation

26

what odontogenic tumors arise in young animals?

odontomas
feline inductive odontogenic tumor

27

what odontogenic tumors is often associated with a deviation from the normal quantity of teeth?

odontoma

28

what are the 2 types of odontomas and what is the difference?

compound: rudimentary tooth-like structures, advanced differentiation
complex: disorderly comglomerate of odontogenic germinal tissues

29

what is apthognomonic for compound odontoma?

denticles

30

what type of dontongenic tumor is often compared to a harmatoma?

compound odontoma