Oesophageal cancer

Question 1

what are the 2 main types

Answer 1

squamous cell carcinoma, adenocarcinoma

Question 2

what is the ratio men : women

Answer 2

2:1

Question 3

which part of the oesophagus is affected in SCC

Answer 3

upper or middle 3rd

Question 4

risk factors SCC

Answer 4

smoking, spirits, diet, chronic oesophagitis, HPV 16 + 18, post menopausal, webbing, Fe deficient anaemia

Question 5

signs

Answer 5

dysphagia, weight loss, retrosternal pain, hoarse cough, aspiration pneumonia, haematemesis, fistula

Question 6

why do you get a hoarse cough in SCC

Answer 6

reccurent laryngeal

Question 7

what part is involved in adenocarcinoma

Answer 7

bottom 3rd- GOJ

Question 8

risk factors adeno

Answer 8

smoking, alcohol, obesity, GORD

Question 9

which is increasing more

Answer 9

adenocarcinoma- assoc with obesity as incr GORD

Question 10

what is Barretts

Answer 10

glandular metaplasia lower 3rd

Question 11

what % of patients with GORD have Barretts

Answer 11

5%

Question 12

outcome predictors

Answer 12

TNM, margin involvement after surgery