Oncological Conditions / Death Flashcards
(34 cards)
Describe the pathophysiology of leukemia (2)
- Overproduction of WBCs
- Immature cells compete causing destruction of normal cells
What are the manifestations of ALL? (3)
- Bone pain
- Bruising
- Pallor
What are the manifestations of AML? (2)
- Anorexia
- Hemorrhage
What complications are associated with leukemia? (3)
- Anemia (decreased RBCs)
- Infection (decreased WBCs)
- Bleeding (decreased platelets)
______ is used for a definitive diagnosis of leukemia
Bone marrow biopsy
______ is used after diagnosis of leukemia to determine CNS involvement
Lumbar puncture
Describe the 3 phases of chemotherapy for leukemia
- Induction - induce complete remission (< 5% of immature cells in bone marrow)
- Consolidation - systemic chemotherapy to eliminate CNS involvement
- Maintenance - maintain remission
______ is used for management of leukemia in addition to chemotherapy
Bone marrow transplantation
Describe the nursing considerations associated with chemotherapy (3)
- Oxygen for hypoxia - prevent anemia
- Neutropenic precautions - prevent infection
- Soft toothbrush, no rectal temps, no needle sticks - prevent bleeding
When is the peak incidence of osteosarcoma?
Adolescent growth spurt - most common near growth plate
What are the manifestations of osteosarcoma? (3)
- Swelling / palpable mass
- Pain with activity / weight bearing
- Limping
What is usually the first clinical manifestation of osteosarcoma?
Fracture
Why is diagnosis of osteosarcoma often late?
Manifestations are similar to normal growth pains
Describe the treatment of osteosarcoma (3)
- Chemotherapy
- Surgical resection
- Amputation - last resort
Metastasis of Wilm’s tumor is most likely to ______
The lung
Describe presentation of Wilm’s tumor
Presentation on one side - usually does not cross the midline
What are the manifestations of Wilm’s tumor? (3)
- Firm / non-tender flank mass
- Hematuria
- Hypertension
What is the primary nursing consideration associated with Wilm’s tumor?
DO NOT palpate the tumor mass - risk of rupture
Describe the treatment of Wilm’s tumor (2)
- Chemotherapy
- Nephrectomy
Where are the most common sites of neuroblastoma? (2)
- Medulla
- Adrenal gland
Why is neuroblastoma known as the “silent tumor”?
Metastasis is common and typically advanced before diagnosis
Treatment of neuroblastoma is dependent on ______
Stage (size, location, metastasis)
Describe the treatment of neuroblastoma (2)
- Chemotherapy / radiation
- Surgical resection
Children of what age are most responsive to treatment of neuroblastoma?
< 1 year old